Results 311 to 320 of about 106,721 (360)

Primary sclerosing cholangitis

Lancet, The, 2018
Primary sclerosing cholangitis is a rare, chronic cholestatic liver disease characterised by intrahepatic or extrahepatic stricturing, or both, with bile duct fibrosis. Inflammation and fibrosis of bile ducts and the liver are followed by impaired bile formation or flow and progressive liver dysfunction.
Jessica K Dyson, Ulrich Beuers, David E J Jones   +2 more
exaly   +4 more sources

Altered faecal microbiome and metabolome in IgG4-related sclerosing cholangitis and primary sclerosing cholangitis

Gut, 2021
Objective Multiple clinical similarities exist between IgG4-related sclerosing cholangitis (IgG4-SC) and primary sclerosing cholangitis (PSC), and while gut dysbiosis has been extensively studied in PSC, the role of the gut microbiota in IgG4-SC remains ...
Qiaoyan Liu, Bo Li, Yikang Li, Yiran Wei, Bingyuan Huang, Jubo Liang, Z. You, You Li, Qiwei Qian, Rui Wang, Jun Zhang, Ruiling Chen, Zhuwan Lyu, Yong Chen, M. Shi, Xiao Xiao, Qixia Wang, Q. Miao, J. Fang, M. Gershwin, M. Lian, Xiong Ma, R. Tang   +22 more
semanticscholar   +1 more source

Global incidence, prevalence and features of primary sclerosing cholangitis: A systematic review and meta‐analysis

Liver international (Print), 2021
Primary sclerosing cholangitis (PSC) is an idiopathic, cholestatic liver disease with a diverse range of clinical manifestations. Inter‐regional data on PSC are variable, but its global geoepidemiology has not been well‐studied.
T. Mehta, S. Weissman, Brian M. Fung, J. Sotiriadis, K. Lindor, J. Tabibian   +5 more
semanticscholar   +1 more source

Sclerosing cholangitis

Baillière's Clinical Gastroenterology, 1997
Primary sclerosing cholangitis (PSC) is a chronic, progressive cholestatic liver disease whose aetiopathogenesis is unknown. PSC is frequently associated with inflammatory bowel disease, in particular chronic ulcerative colitis, is most commonly observed in young males and is clinically characterized by fatigue, pruritus and jaundice.
P J, Marotta, N F, LaRusso, R H, Wiesner
openaire   +2 more sources

Geniposide suppresses liver injury in a mouse model of DDC‐induced sclerosing cholangitis

Phytotherapy Research, 2021
Sclerosing cholangitis, characterized by biliary inflammation, fibrosis, and stricturing, remains one of the most challenging conditions of clinical hepatology. Geniposide (GE) has anti‐inflammatory, hepatoprotective, and cholagogic effects.
Min Wen, Yubei Liu, Ruiying Chen, P. He, Feihua Wu, Rui Li, Yining Lin   +6 more
semanticscholar   +1 more source

Sclerosing cholangitis

Current Opinion in Gastroenterology, 2002
Primary sclerosing cholangitis in children can mimic autoimmune hepatitis in the absence of inflammatory bowel disease. Most adult patients have been identified with human leukocyte antigens that either predispose or protect against disease. Novel class I alleles and cytokine polymorphisms may also contribute to disease susceptibility.
Jayant A, Talwalkar, Keith D, Lindor
openaire   +2 more sources

Oral vancomycin is associated with improved inflammatory bowel disease clinical outcomes in primary sclerosing cholangitis‐associated inflammatory bowel disease (PSC‐IBD): A matched analysis from the Paediatric PSC Consortium

Alimentary Pharmacology and Therapeutics
Data on oral vancomycin for primary sclerosing cholangitis (PSC)‐associated inflammatory bowel disease (IBD) are limited.
A. Ricciuto, Kuan Liu, W. El-Matary, M. Amin, A. Amir, Madeleine Aumar, M. Auth, Matthew D. Di Guglielmo, Eleonora Druve Tavares Fagundes, Alexandre Rodrigues Ferreira, K. Furuya, Nitika A Gupta, Stephen L Guthery, S. P. Horslen, Kyle Jensen, B. Kamath, N. Kerkar, B. G. P. Koot, Trevor J. Laborda, Christine K. Lee, K. Loomes, Cara L. Mack, Mercedes Martinez, A. Montano-Loza, Nadia Ovchinsky, A. Papadopoulou, E. Perito, P. Sakthi Sathya, Kathleen B. Schwarz, Uzma Shah, E. Shteyer, Nisreen Soufi, James Patrick Stevens, Amy E Taylor, M. Tessier, P. Valentino, M. Woynarowski, M. Deneau   +37 more
semanticscholar   +1 more source

Secondary sclerosing cholangitis

Nature Reviews Gastroenterology & Hepatology, 2009
Secondary sclerosing cholangitis (SSC) is a chronic cholestatic biliary disease, characterized by inflammation, obliterative fibrosis of the bile ducts, stricture formation and progressive destruction of the biliary tree that leads to biliary cirrhosis.
Petra, Ruemmele, Ferdinand, Hofstaedter, Cornelia M, Gelbmann   +2 more
openaire   +2 more sources

Primary sclerosing cholangitis

The American Journal of Surgery, 1987
Primary sclerosing cholangitis was seen in only 7 of 6,494 biliary operations performed between 1948 and 1979. Fifteen more cases were seen in 1,467 biliary operations performed over a recent 5 year period. Surgery was directed primarily towards the differential diagnosis between cholangiocarcinoma and primary sclerosing cholangitis of the upper bile ...
T T, White, M J, Hart
openaire   +4 more sources

Primary sclerosing cholangitis

The American Journal of Surgery, 1971
Abstract Primary sclerosing cholangitis is an uncommon condition of unknown etiology, presenting extrahepatic biliary obstruction due to a chronic inflammatory obliterative process. Criteria for diagnosis include progressive biliary obstruction due to a chronic inflammatory fibrous process, absence of biliary stones, absence of biliary surgery prior ...
A W, Perry, E, Djang, G, Kafrouni, L G, Ludington   +3 more
openaire   +2 more sources