Results 41 to 50 of about 84,856 (259)
Primary Sclerosing Cholangitis and Sarcoidosis. Case Report and Review of the Literature
Canadian Journal of Gastroenterology, 1990 A 43-year-old man with longstanding ulcerative colitis developed primary sclerosing cholangitis established by cholangiography and liver biopsy. Within one year of the diagnosis of primary sclerosing cholangitis, pulmonary sarcoidosis developed, proven ...
Gerry N Schep, Linda J Scully
doaj +1 more source
REMEDI: REinforcement learning-driven adaptive MEtabolism modeling of primary sclerosing cholangitis DIsease progression [PDF]
arXiv, 2023 Primary sclerosing cholangitis (PSC) is a rare disease wherein altered bile acid metabolism contributes to sustained liver injury. This paper introduces REMEDI, a framework that captures bile acid dynamics and the body's adaptive response during PSC progression that can assist in exploring treatments.
arxiv
Journal of gastroenterology, 2020 Primary sclerosing cholangitis (PSC) is a progressive liver disease, histologically characterized by inflammation and fibrosis of the bile ducts, and clinically leading to multi-focal biliary strictures and with time cirrhosis and liver failure. Patients
M. Vesterhus, T. Karlsen
semanticscholar +1 more source
Primary sclerosing cholangitis and pregnancy
Clinics and Practice, 2011 Primary sclerosing cholangitis is a progressive disease, and coincidentally in pregnancy it is rare. It is characterized by progressive inflammation and destruction of bile ducts finally resulting in liver failure.
Casper Q. Kammeijer +2 more
doaj +1 more source
Latent class mixed modelling for phenotypic stratification of primary biliary cholangitis patients on first line treatment [PDF]
arXiv, 2022 In patients with primary biliary cholangitis (PBC), the serum liver biochemistry measured during treatment with ursodeoxycholic acid (the UDCA response) accurately predicts long-term outcome. In this study we sought to use liver biochemistry, and in particular alkaline phosphatase (ALP), as a surrogate marker of disease activity, for phenotypic ...
arxiv
Maximum likelihood estimation of hidden Markov models for continuous longitudinal data with missing responses and dropout [PDF]
arXiv, 2021 We propose an inferential approach for maximum likelihood estimation of the hidden Markov models for continuous responses. We extend to the case of longitudinal observations the finite mixture model of multivariate Gaussian distributions with Missing At Random (MAR) outcomes, also accounting for possible dropout.
arxiv
Deep Generative Survival Analysis: Nonparametric Estimation of Conditional Survival Function [PDF]
arXiv, 2022 We propose a deep generative approach to nonparametric estimation of conditional survival and hazard functions with right-censored data. The key idea of the proposed method is to first learn a conditional generator for the joint conditional distribution of the observed time and censoring indicator given the covariates, and then construct the Kaplan ...
arxiv
Primary Sclerosing Cholangitis
Canadian Journal of Gastroenterology, 2000 Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by fibrosing inflammation and obliteration of intra- and/or extrahepatic bile ducts. The disease is one of the most common cholestatic diseases in adults and is diagnosed with increasing frequency. It is very often associated with ulcerative colitis. Patients with
Adolf Stiehl, C. Benz, Peter Sauer
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Comparison of Baseline Covariate Adjustment Methods for Restricted Mean Survival Time [PDF]
arXiv, 2022 The restricted mean survival time is a clinically easy-to-interpret measure that does not require any assumption of proportional hazards. We focus on two ways to directly model the survival time and adjust the covariates. One is to calculate the pseudo-survival time for each subject using leave-one-out, and then perform a model analysis using all ...
arxiv
Journal of Medical Case Reports, 2010 Introduction Although myasthenia gravis is frequently associated with other disorders, it has not been reported together with primary sclerosing cholangitis, complicating the administration of liver-toxic immunosuppressive therapy. Case presentation A 73-
Höflich Sonja, Finsterer Josef
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