Results 241 to 250 of about 922,760 (302)

Advanced MRI Sequences for Structural Lesion Assessment in Sacroiliitis. [PDF]

Diagnostics (Basel)
Özer T, Sönmez EH, Anik Y.
europepmc   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Prevalence, clinical features, and laboratory predictors of autoimmune hepatitis in systemic sclerosis: A retrospective single-center cohort study. [PDF]

Clin Rheumatol
Akar ZA, Yildirim D.
europepmc   +1 more source

The Age‐Dependent Resident Myonuclear Multi‐Omic Response to an Acute Skeletal Muscle Hypertrophic Stimulus in Mice

Advanced Science, EarlyView.
Resident myonuclei are the molecular “control centers” for large multinuclear muscle fibers. It is presumed that, with aging, these control centers become compromised and contribute to delayed or blunted muscle adaptive potential. This study is a detailed roadmap that exposes how young versus aged myonuclei respond to a hypertrophic loading stimulus ...
Pieter J. Koopmans, Ronald G. Jones III, Ana Regina Cabrera, Francielly Morena, Nicholas P. Greene, John J. McCarthy, Ahmed Ismaeel, Yuan Wen, Kevin A. Murach   +8 more
wiley   +1 more source

Periodontal disease and neuroinflammation in multiple sclerosis: a systematic review of current evidence. [PDF]

Front Dent Med
Santhanakrishnan S, Kannappan K, Krithika C, Sridhar C, Mahendra J.   +4 more
europepmc   +1 more source

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy, Zoe L. Chau, Sheng‐You Chen, Nanami Fujisawa, John J. Hill, Barnett M. Hsu, Joanne K. Liu, Karol W. Mai, James J. Lai   +8 more
wiley   +1 more source

Hyaluronidase for microstomia in fibrosing skin disease: Systematic review and case series

JAAD International
Catherine Zhu, MD, Ghassan Barnawi, MD, Elen Grigorchuk, Ethan Bendayan, Katya Peri, MSc, François Lagacé, MD, Houriah Y. Nukaly, MD, Elena Netchiporouk, MD, MSc   +7 more
doaj   +1 more source

A systematic review of therapeutic procedures for the treatment of morphea and systemic sclerosis. [PDF]

Lasers Med Sci
Jafarzadeh A, Leisi A, Goodarzi A.
europepmc   +1 more source

Multidimensional Determinants of Sexual Dysfunction in Multiple Sclerosis: Incremental Insights from a Hierarchical Model. [PDF]

J Clin Med
Sarı Y, Cansel N, Tecellioğlu M.
europepmc   +1 more source

Comparative effectiveness of anti-CD20 therapies and S1P receptor modulators in late-onset multiple sclerosis: real-world evidence from the MSBase registry. [PDF]

Ther Adv Neurol Disord
Surcinelli A, Kalincik T, Roos I, D'Amico E, Lechner-Scott J, Ozakbas S, Hradilek P, Horáková D, Vachova M, Panzera I, Ruzza S, Piscaglia MG, Gerlach O, Meca-Lallana JE, Valero-López G, Kermode AG, Fabis-Pedrini MJ, Prevost J, Ampapa R, Hodgkinson S, Grand'Maison F, Khoury SJ, John NA, Peterka M, Houskova J, Recmanova E, Rous Z, Shaygannejad V, Alroughani R, Kuhle J, Jakob GB, Grammond P, Patti F, Van der Walt A, Butzkueven H, Foschi M.   +35 more
europepmc   +1 more source