Results 101 to 110 of about 1,941 (169)

Inflammatory Mediators Increase Nav1.9 Current and Excitability in Nociceptors through a Coincident Detection Mechanism [PDF]

open access: yes, 2008
Altered function of Na+ channels is responsible for increased hyperexcitability of primary afferent neurons that may underlie pathological pain states.
Clerc, Nadine   +6 more
core   +4 more sources

Characterization of persistent TTX-R Na+ currents in physiological concentration of sodium in rat visceral afferents

open access: yesInternational Journal of Biological Sciences, 2009
Persistent tetrodotoxin-resistant (TTX-R) Na+ (Nav1.9/SCN11A) currents are not normally recorded in vagal afferent neurons (VANs) with 50 mM of extracellular Na+ although the functional expression of this current was observed in the presence of PGE2 or ...
Guo-Fen Qiao, Bai-Yan Li, Yu-Hong Zhou, Yan-Jie Lu, John H. Schild
doaj  

Yield of peripheral sodium channels gene screening in pure small fibre neuropathy

open access: yesJournal of Neurology Neurosurgery & Psychiatry, 2018
Background Neuropathic pain is common in peripheral neuropathy. Recent genetic studies have linked pathogenic voltage-gated sodium channel (VGSC) variants to human pain disorders.
Ivo Eijkenboom   +13 more
semanticscholar   +1 more source

Biodegradable nanoparticles targeting circulating immune cells reduce central and peripheral sensitization to alleviate neuropathic pain following spinal cord injury. [PDF]

open access: yes
Neuropathic pain is a critical source of comorbidity following spinal cord injury (SCI) that can be exacerbated by immune-mediated pathologies in the central and peripheral nervous systems. In this article, we investigate whether drug-free, biodegradable,
Anderson, Aileen   +9 more
core   +1 more source

Sodium channels. [PDF]

open access: yes, 2018
In 2000, with the completion of the human genome project, nine related channels were found to comprise the complete voltage-gated sodium gene family and they were renamed NaV1.1-NaV1.9.
Iseppon, F, Wood, JN
core  

Nav1.9 (SCN11A) [PDF]

open access: yesScience-Business eXchange, 2013
openaire   +1 more source

Neurological perspectives on voltage-gated sodium channels [PDF]

open access: yes, 2016
Abrahamsen   +247 more
core   +1 more source

Blockade of voltage-gated sodium channels inhibits invasion of endocrine resistant breast cancer cells [PDF]

open access: yes, 2016
Al Saleh   +62 more
core   +1 more source

Protein arginine methyltransferase 7 modulates neuronal excitability by interacting with NaV1.9. [PDF]

open access: yesPain, 2022
Ma T   +11 more
europepmc   +1 more source

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