Results 31 to 40 of about 75,659 (315)

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

What Graft Should Be Used in Pediatric Posterior Spinal Fusion? Current Trends and Perspective Among Experts

Journal of the Pediatric Orthopaedic Society of North America
Background: Bone graft use for pediatric posterior spinal fusion (PSF) is highly variable and can lead to additional cost and risk. Biological failures of fusion are rare in children, suggesting that higher-risk grafts used for their perceived efficacy ...
Duby D. Okonkwo, BSc, Stephanie N. Moore-Lotridge, PhD, Jonathan G. Schoenecker, MD, PhD, Amit Jain, MD, MBA, Arun R. Hariharan, MD, John S. Vorhies, MD, Burt Yaszay, MD, Craig R. Louer, Jr., MD, Aaron Buckland, MD, Ahmet Alanay, MD, Amer Samdani, MD, Amit Jain, MD, Baron Lonner, MD, Benjamin Roye, MD, Bob Cho, MD, Burt Yaszay, MD, Caglar Yilgor, MD, Dan Hoernschmeyer, MD, Daniel Hedequist, MD, Daniel Sucato, MD, David Clements, MD, Firoz Miyanji, MD, Harry Shufflebarger, MD, Jack Flynn, MD, Jean Marc Mac Thiong, MD, Josh Murphy, MD, Joshua Pahys, MD, Keith Bachmann, MD, Kevin Neal, MD, Laurel Blakemore, MD, Lawrence Haber, MD, Lawrence Lenke, MD, Mark Abel, MD, Mark Erickson, MD, Michael Glotzbecker, MD, Michael Kelly, MD, Michael Vitale, MD, Michelle Marks, PT, MA, Munish Gupta, MD, Nicholas Fletcher, MD, Noelle Larson, MD, Patrick Cahill, MD, Paul Sponseller, MD, Peter Gabos, MD, Peter Newton, MD, Peter Sturm, MD, Randal Betz, MD, Stefan Parent, MD, Stephen George, MD, Steven Hwang, MD, Suken Shah, MD, Sumeet Garg, MD, Tom Errico, MD, Vidyadhar Upasani, MD   +53 more
doaj   +1 more source

Implementation of a computerized cognitive test to study the body image in adolescents with idiopathic scoliosis

, 2023
openLa presente tesi magistrale si concentra sull'implementazione di un test cognitivo computerizzato per lo studio dell'immagine corporea in adolescenti affetti da scoliosi idiopatica.
ERRAMI, NABIL
core  

Biomechanical Evaluation of Intercostal Muscles in Healthy Children and Adolescent Idiopathic Scoliosis: A Preliminary Study [PDF]

, 2021
Spine deformity during adolescent idiopathic scoliosis can induce a rib-cage deformity. This bone deformity can have direct consequences on the chest-wall muscles, including intercostal muscles, leading to respiratory impairments in individuals with ...
DAVID, Mercedes, VERGARI, Claudio, SKALLI, Wafa, HISAUND, Alisa, PIETTON, Raphaël, LANGLAIS, Tristan, VIALLE, Raphaël   +6 more
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

KINESIOLOGY IN FUNCTION OF THE SKELETAL-MUSCLE DEFORMATION PREVENTION AT SCHOOL AGE [PDF]

Journal of Process Management and New Technologies, 2013
The research is conducted on 1000 male respondents from the eighth grade all the way to the completion of their secondary education. The deviations of the foot and the spinal cord malformations as well as the bad body posture with chest deformities ...
Mitrichka Ks. Stardelova, Dimitrinka K. Conkova , V. Krstevska, Nevenka Panovska , Selim Alili, Angel Dzhambazovski   +5 more
doaj  

PARALYTIC SCOLIOSIS [PDF]

The Journal of Bone and Joint Surgery. British volume, 1956
1. The prognosis of paralytic scoliosis has been studied by defining curve patterns and establishing the natural development as seen in fully grown patients who have not had surgical correction. 2. The prognosis, unlike that in idiopathic scoliosis, is related to the age of onset of the curvature and the degree of muscle imbalance rather than the ...
openaire   +3 more sources

Scoliosis Review : Introduction to an evidence based approach [PDF]

, 2013
Scoliosis is one of the most common diagnoses found in physical therapy practice with idiopathic scoliosis being the most common form found in children.
Rie TAKAKURA
core  

Anesthetic Implications for Scoliosis Surgery

, 2023
Scoliosis is a complex spinal deformity that causes the thoracic rib cage to deform, a lateral curvature of the spine, rotation of the vertebral bodies, and angulation of the ribs. Adolescent idiopathic scoliosis (AIS) is the most prevalent kind.
John, Justin Mathew
core  

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source