Results 201 to 210 of about 104,305,230 (305)

Is painless colonoscopy associated with trainee learning? A single-center study of insertion speed and adenoma detection curves in 1,769 procedures. [PDF]

Front Med (Lausanne)
Ding Y, Wang H, Lin X.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Rethinking chemical clusters: Greenfield and brownfield transition to net-zero by 2050. [PDF]

iScience
Tiggeloven JL, Faaij APC, Kramer GJ, Gazzani M.   +3 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Cross-Cultural Adaptation and Psychometric Evaluation of the Turkish DESTEK (D-SCOPE) Questionnaire: A Multidimensional Assessment of Dietitians' Knowledge, Attitudes and Preparedness Regarding Dietary Supplements in Türkiye. [PDF]

J Hum Nutr Diet
Bilen AB, Çalık A, Demiray PE, Kandemir K, Kalkan GE, Turan Ö, Alphan ME.   +6 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Refining Our Focus by Bridging Theory and Practice for Real-World Impact: An Updated Scope for JMIR Medical Informatics. [PDF]

JMIR Med Inform
Benis A, Iannaccio A, Coristine AJ, Leung TI.   +3 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Greener Choices in Biliary Imaging: A Prospective Carbon Footprint Comparison of Endoscopic Ultrasound Versus Magnetic Resonance Cholangiopancreatography for Intermediate-Likelihood Choledocholithiasis. [PDF]

Clin Transl Gastroenterol
Rughwani H, Jagtap N, de Jong DM, Tyagi A, Putta T, Pasumarthy A, Khair Khan A, Kalapala R, Ramchandani M, Lakhtakia S, Reddy DN.   +10 more
europepmc   +1 more source