Age at menopause and subjective cognitive symptoms predict digital cognitive outcomes at the gynecological Well-Woman visit. [PDF]
Facchetti T +7 more
europepmc +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
All-Inside Posterior Cruciate Ligament Reconstruction Using Achilles Allograft and Suture Tape Augmentation. [PDF]
Md Yusoff BAH +6 more
europepmc +1 more source
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Copper-Mediated Nitrogen-Atom Migration into Saturated Carbocycles. [PDF]
Zeiler MJ +3 more
europepmc +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Operational scope and clinical practice profile of a nurse practitioner-led advanced prostate cancer clinic A retrospective review from a Canadian cancer center. [PDF]
Parezanovic M +5 more
europepmc +1 more source
Oxygen-enabled Fe-catalyzed heteroatom α-C(sp<sup>3</sup>)-H functionalization with nucleophiles. [PDF]
Zhou X +6 more
europepmc +1 more source

