Results 121 to 130 of about 94,820,154 (313)

The Scope, 2010-04, Vol. 05 Num. 06, Issue 102

open access: yes, 2010
The Scope, 2010-04, Vol. 05 Num.

core  

Can supply chains decarbonize? Exploring the potential of scope 3 emission reduction for sustainable transformation

open access: yesSustainable Futures
Scope 3 emissions are the largest and most complex component of corporate carbon footprints, presenting major challenges for decarbonization. This study analyzes a panel dataset of publicly listed European companies (2002–2023) using advanced econometric
AKM Mohsin   +6 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

The Scope, 2011-11, Vol. 07 Num. 10, Issue 124

open access: yes, 2011
The Scope, 2011-11, Vol. 07 Num.

core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The Scope, 2013-11, Vol. 09 Num. 09, Issue 145

open access: yes, 2013
The Scope, 2013-11, Vol. 09 Num.

core  

Revisiting greenhouse gas accounting protocols: a case study on wastewater treatment in Canada

open access: yesEnvironmental Research: Water
Greenhouse gas (GHG) accounting protocols are increasingly used by governments, cities and organizations to quantify their GHG emissions impacts. However, methodological differences between protocols can lead to significant variations in reported ...
Nadine Alzaghrini   +6 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The Scope, 2009-04, Vol. 04 Num. 06, Issue 079

open access: yes, 2009
The Scope, 2009-04, Vol. 04 Num.

core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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