Results 141 to 150 of about 96,425,769 (293)
ABSTRACT Objective Sleep disturbances have been implicated as a risk factor for developing Alzheimer's disease (AD), but evidence linking plasma AD biomarkers to sleep in cognitively unimpaired individuals remains limited. The present study examined associations between evening, morning, and overnight changes in plasma AD biomarkers and measures of ...
Cornelia Sauter +5 more
wiley +1 more source
ABSTRACT Background Blood‐based biomarkers are increasingly used to identify Alzheimer's disease (AD) pathology and may play an important role in early disease screening and participant selection for clinical trials. However, their performance across stages of cognitive impairment remains unclear. This study examined whether plasma biomarkers differ in
Maryam Abdolmaleki +7 more
wiley +1 more source
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos +2 more
wiley +1 more source
DYNAMIC EMPLOYEE EMISSIONS MANAGEMENT CONTROLLER [PDF]
Efforts to reduce greenhouse gas emissions from the transport industry are critical in addressing global emissions. Employee commuting contributes significantly to emissions in the transportation industry (Scope 3 emissions).
Canovai, Tiziano +4 more
core +1 more source
Translating Scope 3 Emission Targets
Företag med stora utsläpp av växthusgaser möter allt starkare krav och förväntningar från olika intressenter, inklusive lagstiftare, att minska sina klimatavtryck. För att möta kraven har många företag börjat sätta upp egna mål för att minska sina egna utsläpp men även för att minska indirekta utsläpp som härrör från företagens leveranskedjor.
openaire +1 more source
Objective The objective of this study was to evaluate the real‐world effectiveness and safety of secukinumab in patients with giant cell arteritis (GCA). Methods This multicenter retrospective study included patients with GCA who received secukinumab at 14 Italian centers with at least six months of follow‐up.
Luca Iorio +28 more
wiley +1 more source
Scope 1, 2 and 3: analysis of their impact in the supply chain
reservedL’aumento delle emissioni inquinanti è attualmente un problema rilevante a livello globale con gravi conseguenze sull’ambiente e per la salute umana, rappresentando una sfida critica che richiede una risposta urgente e coordinata.
RUBEGA, DANIEL
core
dynoGP: Deep Gaussian Processes for Dynamic System Identification
This work introduces a novel class of deep models for system identification, dynamical deep Gaussian processes, which combine the strengths of data‐driven methods, such as those based on neural network architectures, with the ability to output a probability distribution for uncertainty representation.
Alessio Benavoli +3 more
wiley +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source

