Results 61 to 70 of about 96,425,769 (293)

Completeness and Relevance of Scope 3 emissions category across sectors.

open access: yes, 2023
This figure summaries the analyses of completeness and relevance of Scope 3 emissions categories across GICS sectors as described in Section 4.2. Panel (a) presents the completeness based on the proportion of firms that choose to disclose each category ...
Nicholas A. Pittman (17396508)   +5 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Categorization of Scope 3 Emissions for Streamlined Enterprise Carbon Footprinting

open access: yes, 2016
Many organizations look to carbon footprint protocols for guidance on measuring their greenhouse gas emissions, or carbon footprint. Existing protocols generally require estimation of direct emissions (Scope 1) and emissions from direct purchases of ...
Y. Anny Huang (2337916)   +2 more
core   +1 more source

Completeness and Relevance of Scope 3 emissions category over years.

open access: yes, 2023
This figure summaries the analyses of completeness and relevance of Scope 3 emissions categories over years as described in Section 4.2. Panel (a) presents the completeness based on the proportion of firms that choose to disclose each category, panel (b)
Nicholas A. Pittman (17396508)   +5 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Comparing methods for estimating scope 3 waste emissions: a university case study

open access: yesEnvironmental Research Communications
With climate change intensifying and growing concerns over greenhouse gas (GHG) emissions, accurate accounting of emissions has become crucial towards identifying hotspots and opportunities for reduction.
Sofia Abad   +2 more
doaj   +1 more source

Completeness and Relevance of Scope 3 emissions categories over time.

open access: yes, 2023
This table summarises the analyses of completeness and relevance of Scope 3 emissions categories over time as described in Section 4.2. For each category, completeness is measured based on the proportion of firms that choose to disclose each category ...
Nicholas A. Pittman (17396508)   +5 more
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

open access: yesMolecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna   +8 more
wiley   +1 more source

Circular Economy Integration and Carbon Footprint Assessment Across Scopes 1, 2, and 3 of Scrap Based Steel Manufacturing Plant in Saudi Arabia. [PDF]

open access: yesInternational Journal of Environmental Studies and Researches
The steel industry was recognized as a major contributor to global anthropogenic CO2 emissions. Scrap-based electric arc furnace (EAF) technology offered a lower-carbon alternative to the traditional blast furnace–basic oxygen furnace (BF-BOF) route ...
Amin Arafa   +3 more
doaj   +1 more source

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