Results 121 to 130 of about 4,908,765 (311)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Staten: sociologiska perspektiv

Sociologisk Forskning, 1997
Apostolis Papakostas
doaj   +1 more source

Detection and analysis of prompt injection in indian multilingual large language models

Scientific Reports
With the use of Large Language Models (LLMs) becoming more significant in many applications, it has become a great need to ask the question how these LLMs can be made safe and robust, and hence make it behave in an ethical way.
Jagadeesan Srinivasan, Silla Ann Regi, Anbarasa Kumar Anbarasan, Suresh A, Vetriselvi T, Sivakumar Venu   +5 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Remittances and household expenditure patterns in Tajikistan: A propensity score matching analysis [PDF]

The object of this article is to assess the impact of remittances on household expenditure patterns in Tajikistan. More specifically, the paper applies propensity score matching methods to the 2003 Tajikistan Living Standards Measurement Survey.
Matthieu CLEMENT (GREThA, CNRS, UMR 5113)
core  

A simplified clinical risk score predicts the need for early endoscopy in non-variceal upper gastrointestinal bleeding.

, 2014
Background: Pre-endoscopic triage of patients who require an early upper endoscopy can improve management of patients with non-variceal upper gastrointestinal bleeding. Aims: To validate a new simplified clinical score (T-score) to assess the need of an
Riccio E, Anderloni A, Vassallo R, Di Paolo MC, Caserta L, Tammaro L, T. Score Validation Study Group, Zullo A, Hassan C, STURNIOLO, GIACOMO, Natali A, Buda A   +11 more
core   +1 more source

Sick Neonate Score as Predictor of Neonatal Mortality and Duration of Hospital Stay

CHRISMED Journal of Health and Research
Background: Sick neonate score (SNS) is a simple clinical score that requires minimal basic equipment and expertise. It is utilized for the prediction of mortality among neonates. Objective: The objective of this study was to study the correlation of SNS
Prajwal B. Gadgeesh, Neha Agarwal, Sunil Gothwal   +2 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

A silent case of aortic dissection: a case report

Emergency Care Journal
Type B aortic dissection is a relatively rare clinical condition with, however, a significant clinical impact and therefore an early diagnosis is necessary.
Marco Passaretti, Carlo Maino
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source