Diagnostic Significance of Phase-Resolved Functional Lung Low-field Magnetic Resonance Imaging in Comparison to Photon-Counting CT and Pulmonary Function Tests in Connective Tissue Disease-associated Interstitial Lung Diseases. [PDF]
Muecke R +11 more
europepmc +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Longitudinal Response to Epipharyngeal Abrasive Therapy (EAT) in Chronic Nasopharyngitis With Outcome Redefinition and Stratified Analysis by Tissue Type and Baseline Severity. [PDF]
Hirobumi I.
europepmc +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
TST Score Helper: An Open-Source Graphical User Interface for Assisted Manual Scoring of the Tail Suspension Test. [PDF]
Triplett SE +5 more
europepmc +1 more source
This essay looks into the Additive structure relating Sub-scores, which are associated with subscales, to Overall score, which is associated with all testing items. This essay also shows how to calculate the Sub-scores and the Overall score based on the testing item responses of (i) partial credits; (ii) different difficulty levels and (iii ...
openaire +1 more source
Efficient estimation of average treatment effects using the estimated propensity score
K. Hirano, G. Imbens, G. Ridder
semanticscholar +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source

