Results 51 to 60 of about 11,165,306 (334)

Tutorial: a guide to performing polygenic risk score analyses

bioRxiv, 2018
A polygenic score (PGS) or polygenic risk score (PRS) is an estimate of an individual’s genetic liability to a trait or disease, calculated according to their genotype profile and relevant genome-wide association study (GWAS) data.
S. Choi, Timothy Shin Heng Mak, P. O’Reilly   +2 more
semanticscholar   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Modification and Assessment of the Bedside Pediatric Early Warning Score in the Pediatric Allogeneic Hematopoietic Cell Transplant Population [PDF]

, 2018
OBJECTIVES: To determine the validity of the Bedside Pediatric Early Warning Score system in the hematopoietic cell transplant population, and to determine if the addition of weight gain further strengthens the association with need for PICU admission.
Cater, Daniel T., Moser, Elizabeth A.S., Rowan, Courtney M., Tori, Alvaro J.   +3 more
core   +2 more sources

An explainable hybrid framework for early detection of cardiovascular diseases using Categorical Boosting and Bees algorithm

Scientific Reports
Cardiovascular disease (CVD) remains one of the leading causes of death worldwide, claiming millions of lives each year. The early detection of CVD enables healthcare professionals to make informed decisions about the patient’s health.
Jayanta Sen, Sweta Bhattacharya
doaj   +1 more source

Closed-loop sound source localization in neuromorphic systems

Neuromorphic Computing and Engineering, 2023
Sound source localization (SSL) is used in various applications such as industrial noise-control, speech detection in mobile phones, speech enhancement in hearing aids and many more. Newest video conferencing setups use SSL.
Thorben Schoepe, Daniel Gutierrez-Galan, Juan P Dominguez-Morales, Hugh Greatorex, Angel Jimenez-Fernandez, Alejandro Linares-Barranco, Elisabetta Chicca   +6 more
doaj   +1 more source

Protective factors against preterm infants to develop significant patent ductus arteriosus

Pediatrics and Neonatology, 2021
Background: Identifying preterm infants with a higher likelihood of spontaneous patent ductus arteriosus (PDA) closure would be desirable. This study aimed to examine daily PDA status during the first week of life for very low birthweight (VLBW,
Hsiao-Wen Huang, Chih Lin, Kai-Hsiang Hsu, Shih-Yun Hsu, Tze-Yee Mok, I-Hsyuan Wu, Mei-Yin Lai, Reyin Lien   +7 more
doaj   +1 more source

Bruno's Score [PDF]

Journal of Pain and Symptom Management, 2019
Many of our experiences in hospice and palliative care medicine are challenging. We support dying patients and their families as they struggle with the transition from life to death and continue to support those in mourning. Many times, in America, it is difficult to even appreciate a glimmer of spiritual grace as our patients die.
openaire   +2 more sources

Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score

British medical journal, 2020
Objective To develop and validate a pragmatic risk score to predict mortality in patients admitted to hospital with coronavirus disease 2019 (covid-19). Design Prospective observational cohort study.
S. Knight, A. Ho, R. Pius, I. Buchan, G. Carson, T. Drake, J. Dunning, C. Fairfield, C. Gamble, C. A. Green, Rishi K. Gupta, S. Halpin, H. Hardwick, K. Holden, P. Horby, C. Jackson, K. McLean, L. Merson, J. Nguyen-Van-Tam, Lisa Norman, M. Noursadeghi, P. Olliaro, M. Pritchard, C. Russell, Catherine A Shaw, Aziz Sheikh, Tommy Solomon, C. Sudlow, O. Swann, L. Turtle, P. Openshaw, J. Baillie, M. Semple, A. Docherty, E. Harrison, J. Baillie, M. Semple, P. Openshaw, G. Carson, B. Alex, Benjamin Bach, W. Barclay, D. Bogaert, M. Chand, Graham S. Cooke, A. Docherty, J. Dunning, A. da Silva Filipe, T. Fletcher, C. A. Green, E. Harrison, J. Hiscox, A. Ho, P. Horby, S. Ijaz, S. Khoo, P. Klenerman, Andrew Law, W. Lim, A. Mentzer, L. Merson, A. Meynert, M. Noursadeghi, S. Moore, M. Palmarini, W. Paxton, G. Pollakis, NicholasS . C. Price, A. Rambaut, David L. Robertson, C. Russell, V. Sancho-Shimizu, J. Scott, L. Sigfrid, Tommy Solomon, S. Sriskandan, D. Stuart, C. Summers, R. Tedder, E. Thomson, R. Thwaites, L. Turtle, M. Zambon, H. Hardwick, C. Donohue, Jane Ewins, W. Oosthuyzen, Fiona Griffiths, Lisa Norman, R. Pius, Tom M. Drake, C. Fairfield, S. Knight, K. McLean, D. Murphy, Catherine A Shaw, J. Dalton, M. Girvan, Eglė Savičiūtė, S. Roberts, Janet R Harrison, Laura Marsh, M. Connor, S. Halpin, C. Jackson, C. Gamble, G. Leeming, Ross Hendry, James Scott-Brown, W. Greenhalf, V. Shaw, Sarah E. McDonald, K. Ahmed, J. Armstrong, M. Ashworth, I. G. Asiimwe, Siddharth Bakshi, S. Barlow, Laura J. Booth, B. Brennan, K. Bullock, Benjamin W. A. Catterall, Jordan J. Clark, Emily Clarke, Sarah J. Cole, L. Cooper, H. Cox, Christopher Davis, Oslem Dincarslan, Chris Dunn, P. Dyer, A. Elliott, A. Evans, Lewis W S Fisher, T. Foster, Isabel García-Dorival, W. Greenhalf, P. Gunning, Catherine Hartley, A. Ho, R. L. Jensen, Christopher Jones, T. R. Jones, Shadia Khandaker, K. King, Robyn T Kiy, Chrysa Koukorava, Annette Lake, S. Lant, D. Latawiec, L. Lavelle-Langham, Daniella Lefteri, Lauren Lett, Lucia A. Livoti, Maria Mancini, L. McEvoy, J. Mclauchlan, S. Metelmann, Nahida Miah, J. Middleton, Joyce Mitchell, E. Murphy, R. Penrice-Randal, J. Pilgrim, T. Prince, W. Reynolds, P. Ridley, Debby Sales, V. Shaw, R. Shears, B. Small, Krishanthi S Subramaniam, Agnieska Szemiel, Aislynn Taggart, Jolanta Tanianis-Hughes, Jordan Thomas, E. Trochu, Libby van Tonder, Eve Wilcock, J. Zhang, K. Adeniji, D. Agranoff, K. Agwuh, D. Ail, A. Alegria, Brian Angus, A. Ashish, Doug Atkinson, S. Bari, G. Barlow, S. Barnass, Nicholas A. Barrett, C. Bassford, D. Baxter, M. Beadsworth, J. Bernatoniene, J. Berridge, N. Best, P. Bothma, D. Brealey, R. Brittain-Long, N. Bulteel, Thomas G Burden, A. Burtenshaw, Vikki Caruth, D. Chadwick, D. Chambler, Nigel Chee, J. Child, S. Chukkambotla, Tom Clark, P. Collini, Catherine Cosgrove, J. Cupitt, Maria-Teresa Cutino-Moguel, P. Dark, Chris Dawson, S. Dervisevic, P. Donnison, S. Douthwaite, I. DuRand, A. Dushianthan, Tristan Dyer, C. Evans, C. Eziefula, C. Fegan, A. Finn, D. Fullerton, S. Garg, A. Garg, J. Godden, A. Goldsmith, Clive Graham, E. Hardy, S. Hartshorn, D. Harvey, P. Havalda, D. Hawcutt, M. Hobrok, L. Hodgson, Anita Holme, A. Hormis, M. Jacobs, Susan Jain, P. Jennings, A. Kaliappan, V. Kasipandian, S. Kegg, Michael R. Kelsey, J. Kendall, C. Kerrison, I. Kerslake, O. Koch, G. Koduri, G. Koshy, S. Laha, Susan G. Larkin, T. Leiner, P. Lillie, James Limb, V. Linnett, J. Little, M. MacMahon, E. Macnaughton, Ravish Mankregod, Huw Masson, E. Matovu, K. McCullough, R. Mcewen, M. Meda, G. Mills, J. Minton, M. Mirfenderesky, K. Mohandas, Quen Mok, J. Moon, Elinoor Moore, P. Morgan, C. Morris, K. Mortimore, S. Moses, Mbiye A Mpenge, Rohinton Mulla, Michael J. Murphy, Megan L. Nagel, T. Nagarajan, M. Nelson, I. Otahal, M. Pais, S. Panchatsharam, Hassan Paraiso, B. Patel, J. Pepperell, M. Peters, M. Phull, S. Pintus, J. Pooni, F. Post, D. Price, R. Prout, N. Rae, H. Reschreiter, Tim Reynolds, Neil Richardson, M. Roberts, D. Roberts, A. Rose, G. Rousseau, Brendan J. Ryan, Taranprit Saluja, A. Shah, Prad Shanmuga, Anil Sharma, A. Shawcross, J. Sizer, Richard Smith, C. Snelson, N. Spittle, N. Staines, T. Stambach, R. Stewart, P. Subudhi, T. Szakmany, K. Tatham, Jordan Thomas, C. Thompson, R. Thompson, A. Tridente, D. Tupper-Carey, M. Twagira, A. Ustianowski, N. Vallotton, L. Vincent-Smith, S. Visuvanathan, A. Vuylsteke, S. Waddy, R. Wake, A. Walden, I. Welters, T. Whitehouse, P. Whittaker, A. Whittington, M. Wijesinghe, Martin Williams, Lawrence Wilson, S. Wilson, S. Winchester, M. Wiselka, A. Wolverson, D. Wooton, A. Workman, B. Yates, Peter Young   +352 more
semanticscholar   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Family learning: "What's the score?" [PDF]

, 2012
Family Learning through Football and Coaching (FLTFC) was developed with Sunderland Association Football Club (SAFC) Foundation, an adult basic skills provider, a primary school and the Open College Network.
Davison, June
core