Results 51 to 60 of about 188,557 (265)

Risk of Inflammatory Bowel Disease Following Hospital‐Treated Infections and Modulatory Role of Host Genetics to Support a Multi‐Hit Pathogenesis Model

open access: yesAdvanced Science, EarlyView.
Hospital‐treated infections are linked to increased risk of inflammatory bowel disease in a large prospective cohort. This risk differs by infection burden, time since infection, and host immune‐genetic susceptibility. The findings support a multi‐hit pathogenesis model in which severe infection and inherited susceptibility jointly shape inflammatory ...
Haiming Zhuang   +16 more
wiley   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

open access: yesAdvanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori   +10 more
wiley   +1 more source

Delving deeper to come back stronger

open access: yesScottish Journal of Residential Child Care, 2020
For all pupils, the COVID-19 Lockdown has meant a dramatic loss of routine and structure. But for young people in the care system, schools closing often meant the disappearance of their only safe haven and community hub.
Iain MacRitchie
doaj   +1 more source

Engineering Morphological Anisotropy to Control the In Vivo Transport Dynamics, Clearance, and Biodistribution of Silica Nanocarriers

open access: yesAdvanced Science, EarlyView.
Morphological anisotropy directs the in vivo transport under physiological flow and clearance of silica nanocarriers. Increasing anisotropy reduces cellular uptake, suppresses hepatic and splenic sequestration, and prolongs systemic circulation by steering particles toward the central flow core.
Xiaofei Li   +11 more
wiley   +1 more source

Breast cancer secretes anti-ferroptotic MUFAs and depends on selenoprotein synthesis for metastasis

open access: yesEMBO Molecular Medicine
The limited availability of therapeutic options for patients with triple-negative breast cancer (TNBC) contributes to the high rate of metastatic recurrence and poor prognosis.
Tobias Ackermann   +13 more
doaj   +1 more source

Printed Flexible WO3‐Based Supercapacitors for Powering Low‐Powered Electronics in Wearable Devices and Energy Autonomous Temperature Monitoring

open access: yesAdvanced Electronic Materials, EarlyView.
This study represents one of the systematic demonstrations of a screen‐printed, flexible WO3‐based supercapacitor, exhibiting excellent charge‐storage performance for powering wearable electronics. The device shows a specific capacitance of 3.44 F g−1 and an energy density of 0.302 Wh kg−1 at 0.05 mA, which enable to operate multiple wearable ...
Jithin Kanathedath   +6 more
wiley   +1 more source

The Insistence of Blackness and the Persistence of Antiblackness in Ireland

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT This paper positions Ireland as a critical site for examining the insistence of blackness and an antiblackness created and sustained through Irish ethnonationalist imaginaries and exclusionary processes. Drawing on connected sociologies and Irish Black Studies, this enquiry argues that antiblackness in Ireland operates as a generational force,
Philomena Mullen
wiley   +1 more source

Caregiver Reports on the Needs and Experiences of Children Impacted by Parental Incarceration: Results From an Australian Survey

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Children experiencing parental imprisonment are known to be among the most overlooked in our community. They often experience multiple and compounding disadvantages, with long‐term consequences, but receive no specialised assistance. Knowledge about these children and their families is lacking in Australia and is required to inform policy ...
Catherine Flynn   +6 more
wiley   +1 more source

Some patterns of the ‘Murdered Sweetheart Ballads’ in oral tradition, early recordings, and popular culture. [PDF]

open access: yesStudia Ethnologica Pragensia, 2023
Narrative songs with regards to the theme called ‘murdered sweetheart”, are part of a wider repertoire of murder ballads that circulated in England, Scotland, Ireland, and North America. It is through these Murdered Sweetheart Ballads (cf.
Delia Dattilo
doaj  

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