This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Impact of HEIs on the Scottish economy: new evidence from an HEI-disaggregated input-output approach [PDF]
This paper measures the regional demand impacts on output and employment of Scottish Higher Education Institutions (HEIs) based on Input-Output tables for the year 2006.
Hermannsson, K. +3 more
core +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Consumer insurance law - reform at last? [PDF]
Comment by Peter Tyldesley, senior lecturer in the School of Law, University of Bedfordshire, on the prospects of reform in the law governing consumer insurance, following on proposals from the English and Scottish Law Commissions.
Tyldesley, Peter
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The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley +1 more source
The ciliary GTPase Arl13b regulates cell migration and cell cycle progression [PDF]
Acknowledgments We acknowledge Prof. Tamara Caspary from Emory University for kindly providing the cell lines, Linda Duncan from the University of Aberdeen Ian Fraser Cytometry Center for help with flow cytometry.
Clancy, Hannah +6 more
core +2 more sources
Effect of Laser Deoxidation on Adhesive‐Bonded Aluminum in an Oxygen‐Free Atmosphere
This study investigates laser ablation of aluminum under oxygen‐free conditions. The goal is to produce oxide‐free substrates that enable improved adhesive bonding with epoxy. Optimized laser parameters (90% overlap, 300 µJ) combined with oxide‐free substrates result in the highest tensile strength of the adhesive bond.
Sandra Gerland +5 more
wiley +1 more source
Using food intake records to estimate compliance with the Eatwell plate dietary guidelines [PDF]
This work was supported by the Scottish Government's Rural and Environment Science and Analytical Services (RESAS) Division. The original studies, from which the current data were taken, were funded by the Food Standards Agency, UK, and the Biscuit, Cake,
Clark, H. +4 more
core +1 more source
Bioinspired Shape‐Memory Hook Fasteners With Programmable Interlocking and Silent Release
Bioinspired hook fasteners made from epoxy shape‐memory polymers are shown to switch between strong, secure attachment and gentle, silent release when heated. By combining programmable geometry and material response, these adaptive fasteners outperform commercial systems in strength and noise control, enabling new solutions for robotics, medical ...
Maria I. Vallejo Ciro +3 more
wiley +1 more source
The production cycles of the Scottish construction industry, 1802-2002 [PDF]
The revival of Scotland's national Parliament has focussed attention on potential differences in institutions and industries north of the border, compared to the rest of the UK.
Agapiou, Andrew, Baker, Nina
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