Results 51 to 60 of about 20,842 (245)

Human Brain Vasculature‐on‐a‐Chip Model Constructed With Microvessels Isolated From Cryopreserved Postmortem Human Brain Tissue

Advanced Healthcare Materials, EarlyView.
This manuscript describes the cultivation of viable microvessels from cryopreserved human brain tissue. When embedded in hydrogels and cultured in microfluidic devices, these microvessels exhibit complex architectures reminiscent of arterioles and capillaries, can be perfused, and display intact barrier function. Collectively, these results demonstrate
Brian J. O'Grady, A. Scott McCall, Samuel Cullison, Daniel Chavarria, Matthew S. Schrag, Ethan S. Lippmann   +5 more
wiley   +1 more source

Organic matter dynamics in a savanna transition riparian zone: Input of plant reproductive parts increases leaf breakdown process

Journal of Limnology, 2017
The dynamics of coarse particulate organic matter (CPOM) drives the functioning of most low order freshwater ecosystems. We evaluated plant litter input, litterfall, leaf litter breakdown rates, and the aquatic invertebrate community over the course of ...
Renan S. Rezende, Patrícia R.S. Correia, José F. Gonçalves Jr, Anderson M. Santos   +3 more
doaj   +1 more source

Engineering Extracellular Vesicle Production Through Magnetic Ion Channel Activation for Bone Regeneration

Advanced Healthcare Materials, EarlyView.
Magnetic Ion Channel Activation (MICA) enables remote stimulation of mechanosensitive ion channels using functionalised magnetic nanoparticles, enhancing extracellular vesicle (EV) biogenesis is pre‐osteoblasts. MICA desrived EVs exhibit typical nano‐vesicular characteristics but display superior pro‐osteogeneic activity, promoting mesenchymal stem ...
Afeesh Rajan Unnithan, Kenny Man, Kritika, Lee A. Gethings, Christopher J. Hughes, Alicia Keenan, Liam Heaney, Sophie C. Cox, Owen G. Davies, Alicia J. El Haj   +9 more
wiley   +1 more source

Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation

Advanced Healthcare Materials, EarlyView.
This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad, Natasha K. Hunt, Srujan Singh, Kelly B. Seims, Yingjie Wu, E. Thomas Pashuck, Warren L. Grayson, Lesley W. Chow   +7 more
wiley   +1 more source

CONSTRUCTION OF TORSIONAL VIBRATION MECHANICS MODEL OF SCRAPER CONVEYOR AND ANALYSIS OF WORKING CONDITIONS THROUGH BENDING SECTION

Jixie qiangdu, 2022
This article is a study on the physical properties of the scraper under torsion. At first, the process of the scraper conveyor passing through the curved section of the conveyor is analyzed, and then on this basis, the bending moment and the additional ...
MAO Jun, ZHANG YunSheng, XIE ChunXue, LIU ZhiXiang, XIE Miao   +4 more
doaj  

Research on impact characteristics of middle trough of scraper conveyor

Gong-kuang zidonghua, 2019
In order to research impact characteristics of coal materials, scraper and scraper chain on middle trough of scraper conveyor, normal impact load and impact energy during process of coal materials impacting on middle trough were theoretically analyzed ...
WANG Yuan, LI Junxia, WANG Jixin
doaj   +1 more source

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source

Research on the transportation model and coal quantity calculation algorithm of scraper conveyor based on array

Gong-kuang zidonghua
Currently, most research on coal quantity detection focuses on the coal quantity detection and recognition of underground belt conveyors in coal mines. The coal quantity detection of scraper conveyors in fully mechanized working (caving) faces only stays
YIN Rui, ZHANG Dongxue, NI Qiang
doaj   +1 more source

Ultrasound‐Triggered Nanobubbles for Endothelial‐Targeted Drug Delivery in the Detection and Treatment of Doxorubicin‐Induced Cardiotoxicity

Advanced Healthcare Materials, EarlyView.
The DA/VTP‐NBs selectively recognized cardiac ECs damaged by DIC and achieved cell‐level targeted imaging. Then US‐triggered controlled release successfully enabled the release of DAPA within the DA/VTP‐NBs at the site of injury. This precise on‐demand drug release approach amplifies a series of localized therapeutic effects through the mtDNA‐mediated ...
Jun Zhang, Yi Ling, Xin Li, Deng Liu, Li Dong, Xuemei Chen, Yingxin Sun, Yongning Shang, Yanli Guo   +8 more
wiley   +1 more source

Moving mechanism and active control method of scraper conveyor in fully-mechanized mining face

Meitan kexue jishu
In order to study the movement mechanism of the scraper conveyor in the fully-mechanized mining face, the influence of cutting process, working face dip angle and thrust force of hydraulic support on the movement of scraper conveyor are analyzed ...
Fei ZHAO, Feng ZHANG, Quanzhong LI, Dongdong QIN, Hui WEI   +4 more
doaj   +1 more source