Pricing, Popularity, and Customer Satisfaction in Online Pain-Relief Products: An AI-Powered Analysis. [PDF]
Jumreornvong O +12 more
europepmc +1 more source
Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason +12 more
wiley +1 more source
Pediatric massage in conjunction with other traditional Chinese medicine therapies for tic disorder in children: systematic review and network meta-analysis. [PDF]
Liu J +10 more
europepmc +1 more source
This study identifies GDF15+ TAMs as a cell subset mediating tumor regression after immunotherapy. Macrophage‐intrinsic GDF15 enhances phagocytosis and antigen cross‐presentation to CD8+ T cells through the NF‐κB signaling pathway, thereby inhibiting tumor progression.
Xinyu Zhou +9 more
wiley +1 more source
Therapeutic Penetrating Keratoplasty for Aspergillus Fungal Keratitis: A Case Report. [PDF]
Gardeli I, Panagoulis V.
europepmc +1 more source
A novel Bifidobacterium breve strain, Yang08, is isolated to counter its depletion in atopic dermatitis. In mice, live Yang08 requires an intact gut microbiota to exert protection, specifically enriching Akkermansia muciniphila and potently inhibiting pathogenic neutrophil activation and NETosis in the skin.
Yanqiang Shi +6 more
wiley +1 more source
Analysis of scraping therapy intervention plans for lumbar disc herniation
GUO Rongjuan, JIANG Rongrong
doaj
AQP5 Regulates Corneal Nerve Distribution Through NETRIN-1 and SLIT3. [PDF]
Han W +8 more
europepmc +1 more source
Bone Organoids: A Novel Tool for Modeling and Managing Skeletal Disorders in Diabetes
This review synthesizes advances in bone organoid engineering and evaluates their potential to model diabetic bone fragility. Current in vitro and animal models do not fully recapitulate diabetes‐associated skeletal phenotypes. Cell‐based and scaffold‐based bone organoids are discussed as complementary approaches to reconstruct multicellular bone ...
Shuangzhe Lin +2 more
wiley +1 more source
Nasal cytology in the rhinology-allergy clinic: From rhinitis to chronic rhinosinusitis with nasal polyps (CRSwNP). [PDF]
Gelardi M.
europepmc +1 more source

