Results 261 to 270 of about 381,300 (337)

Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation

Advanced Healthcare Materials, EarlyView.
This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad, Natasha K. Hunt, Srujan Singh, Kelly B. Seims, Yingjie Wu, E. Thomas Pashuck, Warren L. Grayson, Lesley W. Chow   +7 more
wiley   +1 more source

Asymmetric lateral habenula function and peripheral neural mechanisms in regulating itch-evoked scratching. [PDF]

Curr Biol
Cranfill SL, Yu H, Wang Y, Inclan-Rico JM, Janke E, Lezgiyeva K, Liu S, Chang A, Gooden S, Baker J, Shirvan S, Wu Q, Bhattarai JP, Hill RZ, Ma M, Luo W.   +15 more
europepmc   +1 more source

Melt Electrowriting High Resolution Poly(ethylene‐co‐vinyl acetate) Scaffolds for Soft Tissue Engineering

Advanced Healthcare Materials, EarlyView.
This work pioneers melt electrowriting (MEW) of polyethylene vinyl acetate (PEVA) to fabricate ultra‐compliant, high‐resolution scaffolds. By integrating microscale precision with soft tissue‐like biomechanics, PEVA overcomes stiffness‐driven limitations of conventional MEW polymers, establishing a mechanically biomimetic platform for soft tissue ...
Finn Snow, Darcy De Rauch, Lilith Mabel Caballero Aguilar, Darcy Millett, Jasley Wilding McBride, David R Nisbet, Magdalena Kita, Elena Pirogova, Robert Michail Ivan Kapsa, Anita Quigley   +9 more
wiley   +1 more source

Calcineurin-NFAT-DSCR1.4 signaling as druggable axis in Gαq-R183Q-driven capillary malformations. [PDF]

Angiogenesis
Xu T, Janssen V, Reinhard NR, Sobrevals-Alcaraz P, van Es RM, de Haan A, de Swart J, Wehrens M, de Kraker H, Wolkerstorfer A, van der Horst CMAM, Vos HR, Huveneers S.   +12 more
europepmc   +1 more source

Sprayable Polymer Blends With Short‐Chain Surface Segregation for Preventing Postoperative Abdominal Adhesions

Advanced Healthcare Materials, EarlyView.
Adhesions’ high occurrence rates and high morbidity render them a critical challenge to be addressed. Current prevention methods, such as physical barriers, have many limitations, resulting in inconsistent safety and efficacy. This study demonstrates the potential for sprayable polymeric materials as an adhesion barrier.
Robert J. Morris III, Tejaswi Nori, Alex I. Halpern, Hannah LaPadula, Arthur V. Cresce, Sarah L. Wright, Anthony D. Sandler, Peter Kofinas   +7 more
wiley   +1 more source

Assessment of the Mechanical Performance of AlCrSiN Coating Implanted with Zr and Ta Ions. [PDF]

Materials (Basel)
Liang J, Ortiz-Membrado L, Bonet R, Orrit-Prat J, Caro J, de Ara JF, Almandoz E, Ruan Q, Fu RK, Chu PK, Llanes L, Jiménez-Piqué E.   +11 more
europepmc   +1 more source

Wound Geometry Determines Whether Aligned‐Fiber Scaffolds Accelerate or Impede Diabetic Wound Healing: A Biased Random Walk Analysis

Advanced Healthcare Materials, EarlyView.
Wound closure is governed by geometry‐orientation coupling: aligned fibers speed migration along their axis but hinder perpendicular advance. In vivo diabetic wound experiments with composition‐matched fibrin, combined with an anisotropic diffusion (biased random‐walk) model, quantify this trade‐off and generate a healing landscape.
Yin‐Yuan Huang, Xiangjun Peng, Yuxuan Huang, Kunkoo Kim, Chengli Li, Peilun Hu, Sean J. Wang, Rohan Avula, Chun‐Yi Yang, Pengchao Ma, Shuhui Yang, Shumeng Jiang, Guy M. Genin, Xiumei Wang   +13 more
wiley   +1 more source

Starting from scratch: Ziermans et al. commentary. [PDF]

Schizophr Res Cogn
Dodell-Feder D, Silverstein SM.
europepmc   +1 more source

Screening of kinase inhibitors in the triple negative KRAS G13D-mutated MDA-MB-231 breast cancer cell line. [PDF]

Sci Rep
Stickler S, Eggerstorfer MT, Rieche M, Arslan S, Teufelsbauer M, Hohenegger M, Weigl L, Hamilton G.   +7 more
europepmc   +1 more source

A progressive fine-tuning framework with dynamic parameter selection for low-resource peptide-GPCR interaction prediction. [PDF]

Brief Bioinform
Liu M, Xu J, Liu J.
europepmc   +1 more source