Results 51 to 60 of about 144,977 (339)
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
Frontiers in Medicine, 2023 BackgroundItch, and thereby the scratching behavior, is a common complaint in atopic dermatitis. Scratching damages the skin, which in turn worsens the itch.
Mathijs R. de Veer +6 more
doaj +1 more source
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
Metals, 2018 The failure of a proximal humerus internal locking system (PHILOS) used in a pantalar arthrodesis was investigated in this paper. PHILOS constructs are hybrids using locking and non-locking screws.
Jason Ina +6 more
doaj +1 more source
Mobility of Edge Dislocations in the Basal‐Slip System of Zinc [PDF]
, 1967 This paper presents the results of measurements of the velocities of 〈1210〉 (0001) edge dislocations in zinc as a function of applied shear stress. All tests were conducted at room temperature on 99.999% pure zinc monocrystals. Dislocations were revealed
Pope, D. P. +2 more
core +2 more sources
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Nocebo Effects and Scratching Behaviour on Itch
Acta Dermato-Venereologica, 2018 Nocebo effects, i.e. reduced treatment effects due to patients’ negative expectations, play a role in itch. Recent studies have shown that nocebo effects can be induced experimentally on itch and also be minimized and even turned into the opposite ...
Danielle J.P. Bartels +3 more
doaj +1 more source
, 2007 A distressed mother attends the clinic with her three year old daughter, who developed an itchy rash. The rash is reddish and affects her face and wrists. The child is restless and has been scratching all night.
Formosa, Marie Claire
core
Proceedings of the AAAI Conference on Artificial Intelligence, 2020 Network pruning is an important research field aiming at reducing computational costs of neural networks. Conventional approaches follow a fixed paradigm which first trains a large and redundant network, and then determines which units (e.g., channels) are less important and thus can be removed.
Wang, Yulong +6 more
openaire +5 more sources
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source