Results 91 to 100 of about 686,597 (304)

Teaching creatively, teaching for creativity : QUT’s Creative Industries Faculty Showcase Panel [PDF]

open access: yes, 2012
In this panel, we showcase approaches to teaching for creativity in disciplines of the Media, Entertainment and Creative Arts School and the School of Design within the Creative Industries Faculty (CIF) at QUT.
Osborne, Lindy
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Risky business: when a CRM vendor masqueraded as an ERP specialist [PDF]

open access: yes, 2007
Taking a social shaping perspective we unpack the development trajectory of a packaged software product to show, that contrary to mainstream accounts, design is not completely specified a-priori and that the process continues throughout implementation,
Griffiths, M, Light, BA
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

L'industria culturale di Adorno e Horkheimer: una proposta di rilettura = The cultural industry of Adorno and Horkheimer: a reinterpretation

open access: yesH-ermes: Journal of Communication, 2013
The essay by Adorno and Horkheimer about The Culture Industry (in the volume Dialectic of Enlightment) represents for Alberto Abruzzese the starting point of a reasoning on the intellectuals' role, the crisis of humanistic and academic knowledge and the ...
Alberto Abruzzese
doaj   +1 more source

Getting down to business: the producer offset five years on [PDF]

open access: yes
  The Producer Offset was introduced in July 2007 as part of the Australian Screen Production Incentive (ASPI), the Australian Government\u27s package of measures to boost support for the Australian film and television industry. One of the key aims

core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Screening for Novel Industrial Biocatalysts

open access: yesEngineering in Life Sciences, 2004
AbstractBiocatalysis, the use of microbial cells or isolated enzymes in the production of fine chemicals, is steadily moving towards becoming accepted as an indispensable tool in the inventory of modern synthetic chemistry [1]. It is estimated that in 10 % of the cases biocatalysis will provide an overall superior synthetic strategy over traditional ...
P. Lorenz, J. Eck
openaire   +1 more source

Remote Real-Time Collaboration Platform enabled by the Capture, Digitisation and Transfer of Human-Workpiece Interactions [PDF]

open access: yes, 2015
In this highly globalised manufacturing ecosystem, product design and verification activities, production and inspection processes, and technical support services are spread across global supply chains and customer networks.
Advikolanu, Yohann   +5 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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