Results 111 to 120 of about 686,597 (304)

The Research of Metro Platform Screen Door Equipotential Bonding and Isolation System

open access: yes机车电传动, 2011
Necessity and functionality of equipotential bonding and isolation treatment were analyzed, and a system solution scheme based on industry technical requirement was provided.
马洪亮
doaj  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Integration of virtual reality within the built environment curriculum [PDF]

open access: yes, 2006
Virtual Reality (VR) technology is still perceived by many as being inaccessible and cost prohibitive with VR applications considered expensive to develop as well as challenging to operate.
Hamza, Neveen, Horne, Margaret
core  

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Artoo-Detoo’s Footprint: Star Wars and the Environmental Impacts of Practical and Digital Filmmaking

open access: yesMedia + Environment
Research on the environmental impacts of screen-media production has typically concentrated on, and tried to mitigate, ecological harms caused by industry practices.
Rebecca Harrison   +1 more
doaj   +1 more source

Making hurricane track data accessible [PDF]

open access: yes, 2010
Our interactive tool allows the exploration, validation and presentation of hundreds of years of dynamically simulated storm tracks. The tracks were generated as part of a research project to improve the risk assessment of tropical storm damage by the ...
Dykes, J.   +4 more
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Prediction of Carbon Emissions Level in China’s Logistics Industry Based on the PSO-SVR Model

open access: yesMathematics
Adjusting the energy structure of various industries is crucial for achieving China’s carbon peak and carbon neutrality goals. Given the significant proportion of carbon emissions from the logistics industry in the tertiary sector, the research on ...
Liang Chen, Yitong Pan, Dongqing Zhang
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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