Results 101 to 110 of about 577 (189)
This thesis seeksto investigate young people's perceptions of their own identities and how the media is used to shapetheir conceptions of self, with specific focus on the understandingsheld by young people themselves. The relationship between media and
Awan, Fatimah
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, 2013 Includes bibliographical references.Due to recent developments in digital video technology, the documentary film format is increasingly being used and adapted in unconventional ways, including in the illustration of research in academia and as an ...
Duff, Kristen Lesley
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Neurodiversity in the screen industries in Ireland
Academic and policy discourse have increasingly recognised the significance of diversity around screen industries. To date, there has been insufficient consideration of neurodivergency as a form of disability in the discussions of diversity within the ...
McSherry, Eleanor
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Roshini Kempadoo - Ghosting: INDIA - Contemporary Photographic and New Media Art
, 2018 An edition of 10 giclée photographic prints (52cm x 102cm) were printed and exhibited in the exhibition FotoFest 2018 Biennial: INDIA - Contemporary Photographic and New Media Art, curated by Sunil Gupta and Steven Evans, Houston, USA.
Kempadoo, Roshini
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Mapping Bristol’s screen industries: Workplace accessibility report
This report summarises findings from a recent case study exploring accessibility provisions and anticipated needs of Deaf, Disabled and / or Neurodivergent media professionals within Bristol’s screen industries.
Genders, Amy
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Stealing Shots: The Heroics and Helplessness of Media Labor
, 2017 There has been increasing scholarship in the anthropology of mass media, with particular attention to the production of film and television (Abu-Lughod 2005; Dornfeld 1998; Ganti 2012; Mandel 2002; Ortner 2013; Pandian 2015).
Martin, SJ
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