Results 201 to 210 of about 7,150,903 (384)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

P001: Discriminating guanidinoacetate methyltransferase enzyme deficiency false positives TPN babies by using the arginine/GUAC ratio*

Genetics in Medicine Open
Alexander Cruz, Kuldeep Dhillon, Jeffrey Aduviso, Jun Qiang Zhou, Long Nguyen, Daniel Simon, Jamie Matteson, Sarah Carter, Tracey Bishop, Rajesh Sharma   +9 more
doaj   +1 more source

Screening and prostate-cancer mortality in a randomized European study.

New England Journal of Medicine, 2009
F. Schröder, J. Hugosson, M. Roobol, T. Tammela, S. Ciatto, V. Nelen, M. Kwiatkowski, M. Luján, H. Lilja, M. Zappa, L. Denis, F. Recker, A. Berenguer, L. Määttänen, C. Bangma, G. Aus, A. Villers, X. Rébillard, T. H. van der Kwast, B. G. Blijenberg, S. Moss, H. D. de Koning, A. Auvinen   +22 more
semanticscholar   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

P042: California's experience with guanidinoacetate methyltransferase enzyme newborn screening on the first 100,000 samples

Genetics in Medicine Open
Kuldeep Dhillon, Jeffrey Aduviso, Jun Qiang Zhou, Long Nguyen, Alexander Cruz, Daniel Simon, Jamie Matteson, Sarah Carter, Tracey Bishop, Rajesh Sharma   +9 more
doaj   +1 more source

ZINC - A Free Database of Commercially Available Compounds for Virtual Screening

Journal of Chemical Information and Modeling, 2005
J. Irwin, B. Shoichet
semanticscholar   +1 more source

High-throughput screening-based design of multifunctional natural polyphenol nano-vesicles to accelerate diabetic wound healing [PDF]

Xiaoying Zhao, Shenkai Su, Chenyu Wu, Yuxin Deng, Yu Chen, Tanxin Yu, Chenchao Li, Yekai Zhang, Xiangyang Wang, Yifei Zhou, Xiaolei Zhang   +10 more
openalex   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Neonatal screening [PDF]

Journal of Tropical Pediatrics, 2014
openaire   +2 more sources

Application of Cancer Screening Guidelines in Resource Limited Settings. [PDF]

Cancer Control
Varghese C, Nongkynrih B, Lohiya A, Prasad A, Barango P.   +4 more
europepmc   +1 more source