Results 311 to 320 of about 7,150,903 (384)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Navigating the Challenges: A Commentary on Barriers to Autism Screening in Childcare Centers. [PDF]

Behav Sci (Basel)
Wieckowski AT, Perez Liz G, McGhee Hassrick E, Koku E, Frick E, Austin A, Robins DL.   +6 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Predicting and identifying correlates of inequalities in breast cancer screening uptake using national level data from India. [PDF]

Front Artif Intell
Tanveer A, Ali RH, Majhi J, Mukherjee M.
europepmc   +1 more source

Identification of Sarcopenic Obesity by Fat-to-Muscle Ratio in Older Adults: A Cohort Study. [PDF]

J Cachexia Sarcopenia Muscle
Kakita D, Harada K, Kurita S, Morikawa M, Nishijima C, Fujii K, Shimada H, Arai H.   +7 more
europepmc   +1 more source

Methods and mechanisms for measuring and monitoring outcomes from newborn bloodspot screening: a scoping review.

Health Technol Assess
Scandrett K, Dinnes J, Morrison B, Coombe A, Agarwal R, Asare IA, Mead P, De Souza A, Elliman D, Lombardo S, Marshall J, Taylor-Phillips S, Takwoingi Y.   +12 more
europepmc   +1 more source

Prevention and early intervention screening for inherited ocular diseases in Saudi Arabia: a national perspective. [PDF]

Front Ophthalmol (Lausanne)
AlEissa MM, Abedalthagafi M, Edward DP.
europepmc   +1 more source

Cost-Effectiveness of Home-Based Self-Sampling vs Clinician Sampling for Anal Precancer Screening.

JAMA Netw Open
Damgacioglu H, McAuliffe TL, Ridolfi TJ, Chiao E, Fernandez ME, Schick V, Smith JS, Brzezinski B, Nitkowski J, Deshmukh AA, Nyitray AG.   +10 more
europepmc   +1 more source

Towards accurate malnutrition identification in individuals with Spinal Cord Injury: a qualitative investigation. [PDF]

Spinal Cord Ser Cases
Keenan SJ, Gunter SI, Meewathurage DC, Desneves KJ.   +3 more
europepmc   +1 more source

Exploring Inclusion in Austria's Breast Cancer Screening:A Dual-Perspective Study of Women with Intellectual Disabilities and Their Caregivers. [PDF]

Int J Environ Res Public Health
Wagner T, Makled N, Scior K, König LM, Unseld M, Zeilinger EL.   +5 more
europepmc   +1 more source