Results 271 to 280 of about 2,434,157 (351)

The Uppsala APP Mutation Promotes Wild‐Type Amyloid‐β Aggregation and Deposition In Vivo

Advanced Science, EarlyView.
We investigated in vivo cross‐seeding of amyloid‐β (Aβ) isoforms in transgenic mice co‐expressing wild‐typeAβ and the Uppsala‐mutant Aβ variant (AβUpp), lacking six central residues. Weleveraged MALDI‐MS imaging and hyperspectral microscopy to follow spatio‐temporalAβ deposition.
Junyue Ge, María Pagnon de la Vega, Silvia Zampar, Enrica Cerilli, Srinivas Koutarapu, Ling Wu, Paul Fraser, Sertan Arkan, Vilmantas Giedraitis, Lars Lannfelt, Greta Hultqvist, Stina Syvänen, Martin Ingelsson, Jörg Hanrieder, Dag Sehlin   +14 more
wiley   +1 more source

Developing provider digital twins for personalized provider-patient communication via a RAG-based conversational framework. [PDF]

Comput Struct Biotechnol J
Li P, Hu Y, Li J, Gemeinhardt G, Li F, Amith M, Cui L, Forte AJ, Tao C.   +8 more
europepmc   +1 more source

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source

Identifying Causal Genes and Building Regulatory Networks in Crops Using the CisTrans-ECAS Method. [PDF]

Bio Protoc
Yan Y, Ming L, Xie W.
europepmc   +1 more source

2D shape dataset of proximity-based spatial relation concepts. [PDF]

Data Brief
Bodnár A, Gulyás L, Kárász Z.
europepmc   +1 more source

Radiomics dataset from chest CT of clinically healthy adults. [PDF]

Data Brief
Bedei V, Ostrovskyy M, Dey N, Kotyk T, Sherratt RS.   +4 more
europepmc   +1 more source

Protein-coding genes in humans and model mammals (mouse, rat and pig): gene identifiers and disambiguation of gene nomenclature retrieved from the Ensembl genome browser. [PDF]

BMC Genomics
Juszczak GR, Pareek CS, Czarnik U, Pierzchała M.   +3 more
europepmc   +1 more source

Correction to: Difficulties in emotion regulation, repetitive negative thinking, and sexual and psychological distress: a two-wave longitudinal mediation study using a transdiagnostic approach. [PDF]

Sex Med
europepmc   +1 more source