Results 51 to 60 of about 924,572 (308)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

The Computer and the Classification of Script [PDF]

open access: yes, 2009
In the 1970s Bernhard Bischoff famously predicted that, thanks to technology, palaeography was on the road to becoming an art of measurement. The journey down this road has not been smooth, however, for several reasons.
Stansbury, Mark
core  

XMDS2: Fast, scalable simulation of coupled stochastic partial differential equations

open access: yes, 2012
XMDS2 is a cross-platform, GPL-licensed, open source package for numerically integrating initial value problems that range from a single ordinary differential equation up to systems of coupled stochastic partial differential equations.
Dennis, Graham R.   +2 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Balinese Script Recognition Using Tesseract Mobile Framework

open access: yesLontar Komputer, 2022
One of the main factors causing the decline in the use of Balinese Script is that Balinese people are less interested in reading Balinese Script because of their reluctance to learn Balinese Script, which is relatively complicated in the recognition ...
Gede Indrawan   +4 more
doaj   +1 more source

Software (Re-)Engineering with PSF III: an IDE for PSF [PDF]

open access: yes, 2007
We describe the design of an integrated development environment (IDE) for PSF. In the software engineering process we used process algebra in the form of PSF for the specification of the architecture of the IDE.
Diertens, Bob
core  

Incidence of components of metabolic syndrome in the metabolically healthy obese over 9 years follow-up: the Atherosclerosis Risk In Communities study. [PDF]

open access: yes, 2017
BackgroundSome obese adults are not afflicted by the metabolic abnormalities often associated with obesity (the 'metabolically healthy obese' (MHO)); however, they may be at increased risk of developing cardiometabolic abnormalities in the future. Little
Bradshaw, PT   +4 more
core   +2 more sources

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Surface electromyographic control of a novel phonemic interface for speech synthesis [PDF]

open access: yes, 2016
Many individuals with minimal movement capabilities use AAC to communicate. These individuals require both an interface with which to construct a message (e.g., a grid of letters) and an input modality with which to select targets.
Cler, Meredith J.   +4 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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