Consideraciones geomorfológías sobre la Sierra Madre Occidental en el norte de Jalisco, México
This analysis of the geographical space focuses on Geomorphology, a science that deals with the genesis and evolution of landforms. This definition includes two basic elements: relief and form. The former results from geological processes, and the latter
Rosier Barrera R.
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THE ROLE OF THE RELIEF IN THE DEVELOPMENT OF HUMAN SETTLEMENTS IN HUŞI DEPRESSION [PDF]
The Role of the Relief in the Development of Human Settlements in Huşi Depression. Human settlements are closely related to the regional physicalgeographical framework determined by the geological, geomorphological, hydrological and climatic features ...
ELENA CHIRILĂ – ACATRINEI
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The Arabian patrimonial industries and crafts,and their role in building the Islamic personality
This research has dealt with some Arab inherited industries and crafts that were implemented in the manner of relief sculpture and the impact of the environment and nature on the Muslim artist, and the role played by the nature and environment in the ...
Salwa El Tahir
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Tracking Trajectories: Projecting Polychromy onto a Roman Relief from a Scottish Castle
The Antonine Wall Distance Sculptures are iconic and unique sculptural reliefs that marked Rome’s most north-westerly frontier across central Scotland. Their inscribed texts and iconography depict graphic tales of frontier life, and recent non-invasive ...
Louisa Campbell
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Multinarasi Relief Yeh Pulu Basis Penciptaan Seni Lukis Kontemporer
Kajian ini merupakan skema penelitian terapan, yang bertujuan untuk mengungkap konsep multinarasi relief Yeh Pulu, Bedulu, Gianyar, Bali, sebagai basis penciptaan seni lukis kontemporer.
I Wayan Adnyana +2 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source

