An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu +7 more
wiley +1 more source
A new Athysanini leafhopper genus from China (Hemiptera, Cicadellidae, Deltocephalinae), with description of two new species. [PDF]
Duan KT, Webb MD, Xing JC.
europepmc +1 more source
Spontaneous Cyclic Levitation of Glycerol‐Water Droplets at Low Pressures
Under low pressure, a minute glycerol addition transforms the chaotic dynamics of freezing water droplets into cyclic levitation. Freeze‐concentration preserves liquid pathways that relax expansion‐induced stress, while freezing point depression weakens asymmetric vaporization recoil.
Chen Xu +10 more
wiley +1 more source
Molecular phylogeny of recognised Thai <i>Landouria</i> species (Gastropoda, Camaenidae), with descriptions of two new species. [PDF]
Nahok B, Chanlabut U, Tanmuangpak K.
europepmc +1 more source
Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen +11 more
wiley +1 more source
Eye tracking deciphers key factors influencing children's implicit visual preferences for street space elements on school commuting routes. [PDF]
Song M, Shang W.
europepmc +1 more source
The analysis of sculpture image classification in utilization of 3D reconstruction under K-means+. [PDF]
Wang X.
europepmc +1 more source
Guardians of the canopy: two new turtle ant species (Hymenoptera: Formicidae: <i>Cephalotes</i>), from Ecuador's Chocó and Amazonia, revealed by morphology and DNA barcoding. [PDF]
Troya A +5 more
europepmc +1 more source
Revision of <i>Acroclisoides</i> Girault & Dodd, 1915 (Chalcidoidea, Pteromalidae, Metasteninae). [PDF]
Tselikh EV +4 more
europepmc +1 more source

