Results 81 to 90 of about 181 (170)

Metabolic conversion of phenol to polyhydroxyalkanoate (PHA) for addressing dual environmental challenges: A review

Current Research in Microbial Sciences
A sustainable approach to microbial polyhydroxyalkanoate (PHA) production involves utilizing waste as a substrate, which can include toxic pollutants like phenol as a carbon feedstock.
Izzati Sabri, Mohd Zulkhairi Mohd Yusoff, Nor Azlan Nor Muhammad, Li Sim Ho, Norhayati Ramli   +4 more
doaj   +1 more source

mTORC2 Phosphorylation of GSDME‐N Drives Cullin4B‐Mediated Proteasomal Degradation to Suppress Pyroptosis and Confer Radioresistance in Small Cell Lung Cancer

Advanced Science, EarlyView.
Radioresistance severely limits the efficacy of therapies for small cell lung cancer (SCLC). This study reveals a novel mechanism of resistance driven by the active suppression of pyroptosis. Specifically, the mTORC2 complex directly phosphorylates GSDME‐N and promotes its CUL4B‐mediated ubiquitination and proteasomal degradation.
Qing‐qing Xu, Ci‐ming Sun, Sui‐xian Zhang, Rui Li, Chen‐fei Wu, Zai‐shan Lin, Li Li, Run‐zhe Chen, Qi‐wen Li, Yuan‐yuan Chen, Xuan Li, Ming Chen   +11 more
wiley   +1 more source

Bioactive Terpenoids from Desert Shrubs for Durable Wood Protection: Chemistry, Delivery Systems, and Circular Bioresource Integration

BioResources
The demand for low-toxicity wood protectants is accelerating the search for plant-derived alternatives. Terpenoids from desert-adapted shrubs combine antimicrobial, insecticidal, hydrophobic, and photoprotective functions yet remain underused in wood ...
Queen Aguma, Ananda Nanjundaswamy, John O. Omolewa, Onyinye P. Choko, Ighoyivwi Onakpoma, Kelechi G. Ibeh, Kufre E. Okon   +6 more
doaj  

Artificial Intelligence‐Based Body Composition Analysis Reveals Sex‐Specific Prognostic Markers and Their Clinical Value in Gastric Cancer: A Multicenter Study

Advanced Science, EarlyView.
This study applied AI to quantify multidimensional body composition from CT images in gastric cancer and healthy controls. Distinct sex‐specific patterns and disease‐related alterations were identified and were associated with survival. Higher muscle and fat measures were linked to improved outcomes.
Tianxiang Li, Tingting Liu, Qian Yang, Zhiqing Zhang, Xiaofang Guo, Xiang Wang, Yihan Zhang, Limin Ge, Yu Su, Wenjun Wu, Weihua Guo, Zheng Wang, Lian Yang, Yanfeng Niu   +13 more
wiley   +1 more source

Identifying opportunities for nature-based solutions with geospatialized life cycle assessments and fine-scale socioecological data

Environmental Research Letters
As we increasingly understand the impact that land management intensification has on local and global climate, the call for nature-based solutions (NbS) in agroecosystems has expanded. Moreover, the pressing need to determine when and where NbS should be
Gabriela Shirkey, Annick Anctil, Ranjeet John, Venkatesh Kolluru, Leah Mungai, Herve Kashongwe, Lauren T Cooper, Ilke Celik, Joshua B Fisher, Jiquan Chen   +9 more
doaj   +1 more source

Resistant Peanut Genotype Reprograms Rhizosphere Metabolism to Enhance Bacterial Wilt Suppression

Advanced Science, EarlyView.
The resistant peanut genotype selectively recruits beneficial bacteria, which coincides with the activation of salicylic acid (SA)‐dependent systemic acquired resistance (SAR) against Ralstonia solanacearum. Keystone rhizosphere metabolites are positively correlated with both beneficial microbiome assembly and SAR gene expression.
Rui Ren, Xiaogang Li, Hao Li, Zenghui Cao, Mengtian Hou, Chunlei Zhao, Nan Lou, Sasa Hu, Yanzhe Li, Qian Ma, Yaoyao Li, Yi Fan, Kunkun Zhao, Kai Zhao, Ding Qiu, Fangping Gong, Zhongfeng Li, Haitao Liu, Xingli Ma, Xingxiang Wang, Dongmei Yin   +20 more
wiley   +1 more source

Natural assets, changes, and variations of the socioeconomic-environmental systems along the Asian drylands belt

Environmental Research: Ecology
The amount of and changes in a country’s natural assets are crucial for developing national strategic plans and policies due to their foundational role in determining the resilience of social-environmental systems (SES), especially under a changing ...
Jiquan Chen, Ranjeet John, Venkatesh Kolluru, Elizabeth A Mack, Peilei Fan, Jing Yuan, Zutao Ouyang, Jingyan Chen, Pavel Groisman, Changliang Shao, Amarjargal Amartuvshin, Garik Gutman   +11 more
doaj   +1 more source

Multi‐Stimuli‐Responsive Hydrogen‐Bonded Organic Frameworks Nanocarriers Enable Targeted Fungicide Release and Plant Immune Regulation

Advanced Science, EarlyView.
A fluorinated hydrogen‐bonded organic framework nanocarrier (PFC‐1‐F) loaded with PYR and coated with HACC enables multi‐stimuli‐responsive (enzyme/ROS/pH) release at infection sites. Exhibiting targeted antifungal activity against Sclerotium rolfsii, modulating plant antioxidant defense, and demonstrating favorable biosafety across plant, soil, and ...
Guangming Ma, Ying Zou, Yao Wang, Huiyan Li, Jinlin Li, Tianfu Liu, Xiaohong Pan   +6 more
wiley   +1 more source

PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression

Advanced Science, EarlyView.
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian, Yifan Cheng, Jiajie Zhou, Ruiqi Li, Shuai Zhao, Ben Li, Zijie Xu, Mengli Zi, Yayan Fu, Chenkai Zhang, Qiannan Sun, Shantanu Baral, Sen Wang, Daorong Wang   +13 more
wiley   +1 more source

Trend analysis of precipitation and temperature in Lahaul-Spiti district, Himachal Pradesh, India

Frontiers in Climate
Lahaul-Spiti district is a cold desert mountain, situated in the Trans-Himalayan region. The district has the lowest population density of 2 persons/km2 because of the harsh climate and rough topography that act as barriers to population growth. Specific
Pankaj Kumar, Dhanjit Deka, Md. Arif Husain, Manish Kumar, Pandurang Choudhari, Shipra Singh, Azka Kamil, Abhishek Banerjee   +7 more
doaj   +1 more source