Results 171 to 180 of about 29,999 (260)

TRIM32 controls timely cell cycle exit in muscular differentiation through downregulation of c‐Myc mRNA

open access: yesThe FEBS Journal, EarlyView.
Trim32 regulates the transition from proliferation to differentiation in C2C12 cells after myogenic induction. We found that, at the onset of differentiation, Trim32 destabilizes c‐Myc mRNA, promotes cell cycle exit, and enables normal myotube formation.
Lu Xiong   +6 more
wiley   +1 more source

Rescue of pATOM36‐depleted T. brucei by human MTCH1/2 reveals common features of protein insertases

open access: yesThe FEBS Journal, EarlyView.
Human MTCH1 and MTCH2 (with an N‐terminal extension) functionally complement the loss of pATOM36 in T. brucei, indicating that these evolutionarily distant proteins recognize a common set of substrates and share fundamental principles of mitochondrial outer membrane protein insertion. Structural analyses reveal a common hydrophilic cavity, supporting a
Stephan Berger   +4 more
wiley   +1 more source

The H19/miR‐760/BST2 regulatory axis sustains breast cancer tumorigenesis and metastasis

open access: yesThe FEBS Journal, EarlyView.
H19 and BST2 promote breast cancer aggressiveness through their reciprocal coregulation by miR‐760. Since both transcripts are targeted by miR‐760, overexpression of one sequesters the microRNA and relieves repression of the other: H19 raises BST2 levels, and BST2 raises H19 levels.
Kekely Klouyovo   +8 more
wiley   +1 more source

Assessing fidelity of interventions to foster shared decision making in clinical encounters: Development of an implementation-focused fidelity checklist for use with electronic conversation aids. [PDF]

open access: yesPEC Innov
Ridgeway JL   +11 more
europepmc   +1 more source

Divergent Environmental Niches and Climate Vulnerabilities of Jonah Crab (Cancer borealis) and Atlantic Rock Crab (Cancer irroratus)

open access: yesFisheries Oceanography, EarlyView.
ABSTRACT Jonah crab and Atlantic rock crab in the United States are currently assessed by National Oceanic and Atmospheric Administration climate change vulnerability assessments under the category Cancer crabs due to a dearth of species‐specific information across the attributes assessed.
Everett J. Rzeszowski   +2 more
wiley   +1 more source

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