Results 31 to 40 of about 134,212 (158)

Oxidative Stress: A Pathogenic Mechanism for Niemann‐Pick Type C Disease

open access: yesOxidative Medicine and Cellular Longevity, Volume 2012, Issue 1, 2012., 2012
Niemann‐Pick type C (NPC) disease is a neurovisceral atypical lipid storage disorder involving the accumulation of cholesterol and other lipids in the late endocytic pathway. The pathogenic mechanism that links the accumulation of intracellular cholesterol with cell death in NPC disease in both the CNS and the liver is currently unknown.
Mary Carmen Vázquez   +4 more
wiley   +1 more source

La señalización, un tema turístico. El caso de la señalización de las autopistas para "actividades culturales y turísticas”

open access: yesVia@
¿Puede el turismo prescindir de autores y diseñadores? Esta es la pregunta que surge ante un cartel de autopista para "actividades culturales y turísticas" representado por los "carteles marrones" desplegados en nuestras autopistas.
Benoît Berthou
doaj   +1 more source

Señalización y seguridad vial [PDF]

open access: yes, 1992
Se explica el suceso de que un autobús con 55 pasajeros se salió de la autopista y sufrió un accidente, se pide que se esclarezcan los hechos y que se dote de mejor señalización a las carreteras ...
García Verduch, Antonio
core  

“INEVITABILITY”: Capturing Strategic Ambiguity in Xi Jinping's China

open access: yesWorld Affairs, Volume 188, Issue 2, Summer 2025.
ABSTRACT This article approaches the discourse of inevitability used by Xi Jinping and his foreign policy communicators from the perspective of strategic ambiguity signaling. Drawing on the post‐realist rhetoric turn, it analyzes its roots, evolution, as well as the contexts in which Xi Jinping deploys it, most notably in relation to the “great ...
Una Aleksandra Bērziņa‐Čerenkova
wiley   +1 more source

Papel de la proteína supresora de la señalización por citocinas-3 (SOCS 3) en la resistencia a la hormona de crecimiento inducida por malnutrición.

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2003
La nutrición es un regulador importante de las acciones de la hormona de crecimiento (GH). Se ha demostrado que el déficit de nutrientes induce un estado de resistencia a la hormona, en el cual están involucrados, entre otros factores, alteraciones post ...
Adriana Umaña   +2 more
doaj   +1 more source

Glucose prevents the acquisition of the capacitated state in pig spermatozoa

open access: yesAndrology, Volume 13, Issue 3, Page 637-649, March 2025.
Abstract Background Mammalian spermatozoa need to undergo a process named capacitation to be able to fertilize an oocyte. During their journey in the female tract, spermatozoa obtain energy while exposed to a changing environment containing a variety of metabolic substrates. The energy requirements for sperm capacitation are species‐specific.
Rebeca Serrano   +6 more
wiley   +1 more source

Heteroreceptor complexes and their allosteric receptor-receptor interactions in the central nervous system. Focus on examples from Dopamine D2 and Serotonin 5-HT1a receptors [PDF]

open access: yes, 2018
GPCR interacting proteins (specially β- arrestin) and their receptor-protein interactions are also covered but their interactions with the allosteric receptor-receptor interactions in heteroreceptor complexes remain to be elucidated.
Corrales Ferro, Fidel
core   +1 more source

Prolonged incubation of frozen–thawed equine spermatozoa for in vitro fertilization: A preliminary study using low temperature and INRA96 medium

open access: yesReproduction in Domestic Animals, Volume 59, Issue S3, October 2024.
Abstract A protocol for conventional in vitro fertilization (IVF) in horses using fresh semen has been described, using a prolonged incubation in FERT‐TALP medium (22 h) at 38.2°C in the presence of penicillamine, hypotaurine and epinephrine (PHE).
Marcos Luis‐Calero   +4 more
wiley   +1 more source

RGS14 (414)-mediated prevention of an episodic memory loss: a study of molecular mechanism [PDF]

open access: yes, 2015
A large proportion of human populations suffer memory impairments either caused by normal aging or afflicted by diverse neurological and neurodegenerative diseases. Memory enhancers and other drugs tested so far against memory loss have failed to produce
Navarro Lobato, Irene
core   +1 more source

A new hormonal protocol supports early development of in vitro‐produced embryos after transfer to anoestrus mares

open access: yesReproduction in Domestic Animals, Volume 59, Issue S3, October 2024.
Abstract The present study aimed to evaluate whether primed anoestrus mares are suitable recipients for embryos produced by intracytoplasmic sperm injection (ICSI). Anoestrus was confirmed in four mares and daily doses of oestradiol benzoate (6 mg in total) over 5 days were administered; after 3 days of rest, oral altrenogest was administered at 0.088 ...
Carmen C. Muñoz‐García   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy