Results 221 to 230 of about 25,164,155 (279)

Five‐Grass‐Pollen Sublingual Immunotherapy Drops Are Efficacious and Well Tolerated in Adults: The RHAPSODY Phase III Trial

open access: yesAllergy, EarlyView.
The RHAPSODY multinational study investigated 26 months of continuous treatment with 5‐grass‐pollen sublingual SLIT drops in adults with moderate‐to‐severe grass‐pollen‐induced allergic rhinoconjunctivitis. The primary efficacy endpoint (the average daily total combined score) showed statistically significant differences in favour of the active ...
Alain Didier   +4 more
wiley   +1 more source

International Guideline on the Diagnosis and Management of Pediatric Patients With Hereditary Angioedema

open access: yesAllergy, EarlyView.
ABSTRACT Hereditary angioedema (HAE) with C1 inhibitor deficiency is a rare disease characterized by unpredictable episodes of tissue swelling (angioedema), which, in most cases, occur first under the age of 18 years, and entail a significant burden of disease not only for the patients but also for their families.
Henriette Farkas   +128 more
wiley   +1 more source

Effects of vaginal microbiota transfer on social–emotional and neurodevelopment in cesarean‐born infants: 12‐month follow‐up of a pilot randomized clinical trial

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
In a pilot randomized clinical trial of cesarean‐born infants, vaginal microbiota transfer improved social–emotional development at 12 months, reducing social–emotional risk and improving key subdomains, while early neurodevelopmental benefits observed at 6 months were not sustained at 12 months. Abstract Introduction To evaluate the effects of vaginal
Chuhui Zhou   +9 more
wiley   +1 more source

The Effect of Adenotonsillectomy on Sleep Efficiency in Pediatric Patients. [PDF]

open access: yesLaryngoscope Investig Otolaryngol
Mansoor BS   +4 more
europepmc   +1 more source

Seladelpar Improved Itch, Itch‐Related Sleep Disturbance and Measures of Fatigue in Patients With Primary Biliary Cholangitis and Pruritus in the Phase 3 RESPONSE Trial

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Seladelpar improved itch, itch‐related sleep disturbance and measures of fatigue in patients with primary biliary cholangitis and pruritus in the Phase 3 RESPONSE trial. ABSTRACT Background Pruritus and fatigue impose a significant burden on patient quality of life in primary biliary cholangitis (PBC).
Cynthia Levy   +10 more
wiley   +1 more source

Application of CRISPR/Cas13a system on the rapid detection of Salmonella spp. [PDF]

open access: yesPLoS Negl Trop Dis
Huang Y   +7 more
europepmc   +1 more source

One‐Year Effectiveness of Upadacitinib in Perianal Crohn's Disease: A Real‐World GETAID Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In a real‐world cohort of patients with highly refractory perianal Crohn's disease, upadacitinib induced clinical remission at 12 months in 26% of patients with fistulizing disease and 25% of those with isolated anal ulcerations. ABSTRACT Introduction Upadacitinib (UPA) is effective for treating luminal Crohn's disease (CD), but data on perianal CD ...
Nicolas Richard   +13 more
wiley   +1 more source

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