Results 161 to 170 of about 10,366,637 (362)

A 52‐week open‐label extension study to evaluate the safety and efficacy of oral rimegepant for the preventive treatment of migraine

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To assess the safety, tolerability, and treatment effects of rimegepant 75 mg every other calendar day (EOD) for the preventive treatment of migraine in a 52‐week, open‐label extension (OLE) study. Background Rimegepant is an oral small molecule calcitonin gene–related peptide receptor antagonist approved for the acute treatment of ...
David Kudrow   +3 more
wiley   +1 more source

Europe sociale et Europe de l'emploi : l'apport de Douglass North à l'explication des trajectoires nationales [PDF]

open access: yes
Les évolutions des politiques sociales et des politiques de l'emploi en Europe posent des enjeux complexes d'analyse : en effet, les systèmes de protection sociale et de politique de l'emploi se caractérisent par la persistance de trajectoires ...
Bruno Palier, Christine Erhel
core  

Comprehensive assessment of erenumab efficacy in participants with high‐frequency episodic migraine with at least one previously failed preventive treatment: The EMBRACE study

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To evaluate the effect of erenumab treatment beyond monthly migraine days in patients with high‐frequency episodic migraine who did not respond to at least one previous migraine preventive treatment. Background Reduction in monthly migraine days has been the efficacy standard for migraine preventive treatments; however, it does not ...
Gabriel Paiva da Silva Lima   +11 more
wiley   +1 more source

Evaluating the quality of society and public services [PDF]

open access: yes, 2010
A person’s quality of life is not only shaped by individual choices and behaviour: the surrounding environment and the public services on offer have a big influence on how people perceive the society they live in and on their evaluation of their own ...
Newton, Kenneth, Rose, Richard
core  

Effectiveness and safety of two‐drug regimens containing an integrase inhibitor and reverse transcriptase inhibitor in a cohort of virologically suppressed people with HIV: Data from the COMBINE‐2 study

open access: yesHIV Medicine, EarlyView.
Abstract Objectives This study assessed real‐world effectiveness and safety of switching to dual therapy regimens consisting of an integrase inhibitor (INSTI), and reverse transcriptase inhibitor (RTI), among suppressed people living with HIV in Europe.
Cristina Mussini   +24 more
wiley   +1 more source

Repetition of attempted suicide among immigrants in Europe [PDF]

open access: yes, 2014
Objectives: To compare frequencies of suicide attempt repetition in immigrants and local European populations, and the timing of repetition in these groups.
Apter, Alan   +9 more
core  

Exploring the impact of Cabotegravir‐Rilpivirine long‐acting on weight gain, body composition and quality of life in adults living with HIV

open access: yesHIV Medicine, EarlyView.
Abstract Introduction Long‐acting injectable antiretroviral therapy (ART) with Cabotegravir (CAB) and Rilpivirine (RPV) offers an alternative to daily oral regimens, improving adherence and patient satisfaction. However, its impact on body composition and metabolism remains underexplored.
Andrea De Vito   +13 more
wiley   +1 more source

Development and validation of PBPK models for genistein and daidzein for use in a next-generation risk assessment

open access: yesFrontiers in Pharmacology
IntroductionAll cosmetic ingredients must be evaluated for their safety to consumers. In the absence of in vivo data, systemic concentrations of ingredients can be predicted using Physiologically based Pharmacokinetic (PBPK) models.
A. Najjar   +8 more
doaj   +1 more source

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