Results 251 to 260 of about 10,366,637 (362)

An Evaluation of the Drug Interaction Potential of Encorafenib in Combination With Binimetinib Using the Inje Cocktail in Patients With Cancer

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 2, Page 375-380, February 2026.
A clinical drug–drug interaction (DDI) study was designed to evaluate the effect of single and multiple oral doses of encorafenib on the single oral dose pharmacokinetics (PK) of the cytochrome P450 (CYP) enzyme probe substrates, losartan (CYP2C9), midazolam (CYP3A4), caffeine (CYP1A2), omeprazole (CYP2C19), and dextromethorphan (CYP2D6) administered ...
Joseph Piscitelli   +6 more
wiley   +1 more source

Monitored hygrothermal dataset of a high-altitude Dolomite refuge: wall and indoor climate at 2870 m a.s.l. [PDF]

open access: yesSci Data
Panico S   +6 more
europepmc   +1 more source

Variable origin of clinopyroxene megacrysts carried by Cenozoic volcanic rocks from the eastern limb of Central European Volcanic Province (SE Germany and SW Poland)

open access: hybrid, 2020
Magdalena Matusiak‐Małek   +7 more
openalex   +1 more source

Performance Evaluation of Rice Bran Oil—Waste Cooking Oil Binary Blend‐Based Biodiesel With Normal Diesel in CI Engine

open access: yesEngineering Reports, Volume 8, Issue 2, February 2026.
This study evaluates the performance and emissions of CI engines using biodiesel blends derived from rice bran and waste cooking oil, revealing that a 30% biodiesel blend significantly reduces emissions, while a 70% blend affects specific engine parameters. ABSTRACT This research investigates the performance, combustion, and emission characteristics of
S. Prathap Singh   +6 more
wiley   +1 more source

L’esclave, ses cousins et ses héritiers (Europe, Afrique, Caraïbes, et ailleurs)

open access: yesAnnuaire de l'EHESS, 2004
Vincent, Bernard   +3 more
openaire   +1 more source

A Phase 1 Study of the Pharmacokinetics, Safety, and Tolerability of Posdinemab (JNJ‐63733657) in Healthy Chinese Adults

open access: yesThe Journal of Clinical Pharmacology, Volume 66, Issue 2, February 2026.
Abstract Posdinemab, a humanized immunoglobulin G1/κ monoclonal antibody, binds with high affinity to phosphorylated tau protein which is associated with Alzheimer's disease (AD) pathophysiology. Posdinemab reduced tau seeding in murine models and was well tolerated in Phase‐1 clinical studies.
Fangfang Wang   +7 more
wiley   +1 more source

Reasoning‐optimised large language models reach near‐expert accuracy on board‐style orthopaedic exams: A multi‐model comparison on 702 multiple‐choice questions

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, Volume 34, Issue 2, Page 752-762, February 2026.
Abstract Purpose The purpose of this study was to compare the accuracy, calibration, reproducibility and operating cost of seven large language models (LLMs)—including four newer models capable of using advanced reasoning techniques to analyse complex medical information and generate accurate responses—on text‐only orthopaedic multiple‐choice questions
Pedro Diniz   +5 more
wiley   +1 more source

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