Results 181 to 190 of about 86,741 (265)

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

Advanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang, Baoshuai Liang, Liangmin Fu, Weiliang Deng, Yuyan Jiang, Weiping Xu, Jinwei Chen, Ya Zhou, Ke Wu, Jiaguo Huang   +9 more
wiley   +1 more source

Ancient forests help document the long-term impacts of climate change. [PDF]

Proc Natl Acad Sci U S A
Anderson DG.
europepmc   +1 more source

Observation and modelling of superimposed ice formation on summery sea ice in Antarktica [PDF]

, 2003
Haas, Christian, Nicolaus, Marcel
core  

A Hydrogen‐Releasing Nanozyme Engineers a Mitochondrial ROS Amplifier for Self‐Sustaining Catalytic Immunotherapy

Advanced Science, EarlyView.
We developed a RhPd‐H nanozyme that integrates enhanced POD‐mimetic catalytic activity with thermally triggered H2 release. H2 shields and reprograms mitochondria to continuously leak endogenous ·O2−. This dual‐path ROS spatially and temporally disrupts redox homeostasis, inducing persistent oxidative stress for tumor suppression and antitumor immunity,
Mingfan Shi, Jingrui Cao, Tong Wu, Guang Yang, YaWen Yang, Shixin Zhang, Wenwen Su, Hongyu Chu, Yangyang Zhao, Shan Jiang, Qiong Wu, Dongxu Jiao, Fangfang Chen   +12 more
wiley   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Tracing the origin of tropical North Atlantic <i>Sargassum</i> blooms to West Africa. [PDF]

PNAS Nexus
Beron-Vera FJ, Olascoaga MJ, Miron P, Bonner G.   +3 more
europepmc   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Enhanced deep Southern Ocean stratification during the lukewarm interglacials. [PDF]

Nat Commun
Huang H, Fietzke J, Gutjahr M, Frank M, Kuhn G, Zhang X, Hillenbrand CD, Li D, Hu J, Yu J.   +9 more
europepmc   +1 more source

Unlocking Plant‐Derived Potential: Regulating Microcrystalline Structure Design of High‐performance Hard Carbon Anodes via Cellulose Molecules

Advanced Science, EarlyView.
The microcrystalline structure of hard carbon derived from green sandalwood is modulated by controlling the steric hindrance effect of the precursor, thereby significantly enhancing ion diffusion kinetics. When utilized in sodium‐ion batteries, it demonstrates excellent cycle life, exceeding 7000 cycles, as well as superior low‐temperature performance,
Xiping Zhang, Wenhao Yang, Dan You, Ziyi Zhu, Xue Li   +4 more
wiley   +1 more source

Spatial overlap of sea ice-associated predators and prey in western Hudson Bay. [PDF]

PLoS One
Warret Rodrigues C, Derocher AE, Roth JD, McGeachy D, Pilfold NW.   +4 more
europepmc   +1 more source