Results 181 to 190 of about 4,885,951 (328)

North Atlantic Ocean Circulation and Decadal Sea Level Change During the Altimetry Era. [PDF]

open access: yesSci Rep, 2019
Chafik L   +4 more
europepmc   +1 more source

Quaternary sea level change in Scotland

open access: yesEarth and environmental science transactions of the Royal Society of Edinburgh, 2019
David E. Smith   +6 more
semanticscholar   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

10,000 years of centennially-resolved climate and sea-level change archived in Svalbard beach-ridge system. [PDF]

open access: yesSci Rep
Strzelecki MC   +5 more
europepmc   +1 more source

Postglacial relative sea level change and glacier activity in the early and late Holocene: Wahlenbergfjorden, Nordaustlandet, Svalbard. [PDF]

open access: yesSci Rep, 2019
Schomacker A   +9 more
europepmc   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Impact of glacial/interglacial sea level change on the ocean nitrogen cycle. [PDF]

open access: yesProc Natl Acad Sci U S A, 2017
Ren H   +8 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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