Results 261 to 270 of about 4,885,951 (328)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

North American ice sheet persistence into past interglacials should inform future projections. [PDF]

Nat Commun
Creel RC, Kopp RE, Dutton A, Zhou Y, Raymo ME, Britt CJ, DeConto RM.   +6 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Population Structure and Genetic Diversity Analyses Reveal Isolation That May Imperil the Northernmost Colony of the Endangered Australian Sea Lion. [PDF]

Ecol Evol
Morris V, Chariton A, Harcourt R, Grueber CE, Charrier I, Raudino H, Waples K, Kirkwood R, Goldsworthy SD, Pitcher BJ.   +9 more
europepmc   +1 more source

A Study of Absolute Pressure Inside the Cabins of Land Transport Vehicles-The Concept of a Ventilation System Regulating the Pressure in the Vehicle. [PDF]

Sensors (Basel)
Teleszewski TJ, Gładyszewska-Fiedoruk K.   +1 more
europepmc   +1 more source

Detection and Emergence of Climate Change Signals in Extreme Sea Levels: A Global-scale Analysis

Nawarat K, Tebaldi C, Reyns J, Muis S, Ranasinghe R.   +4 more
europepmc   +1 more source

Long-term hydrodynamic changes in marginal estuarine seas: the role of sea level rise and freshwater fluxes. [PDF]

Sci Rep
Stanev EV.
europepmc   +1 more source

Analysis of urban resilience assessment and spatiotemporal patterns in coastal cities under sea-level rise. [PDF]

Sci Rep
Liang B, Shi G, Wu H, Qu S, Wang M, Sun Z.   +5 more
europepmc   +1 more source

A global assessment of coastal vulnerability and dominant contributors. [PDF]

Nat Commun
Basnayake V, Duong TM, Ranasinghe R, Almar R, Wijnberg KM.   +4 more
europepmc   +1 more source

Distance to a Drying Saline Lake and Lung Function Development in a Rural Border Cohort of Children.

JAMA Netw Open
Guo F, Kamai EM, Eckel SP, Barahona DD, Olmedo L, Bejarano E, Torres C, Zuidema C, Seto E, Farzan SF, Johnston JE.   +10 more
europepmc   +1 more source