Results 161 to 170 of about 2,485,692 (404)

A sea of ice

open access: yes, 2011
Peer ...
Dachs, Ramón   +3 more
openaire   +1 more source

Winter storms accelerate the demise of sea ice in the Atlantic sector of the Arctic Ocean

open access: yesScientific Reports, 2019
A large retreat of sea-ice in the ‘stormy’ Atlantic Sector of the Arctic Ocean has become evident through a series of record minima for the winter maximum sea-ice extent since 2015.
Robert M. Graham   +31 more
semanticscholar   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Glacial/interglacial changes in mineral dust and sea-salt records in polar ice cores: sources, transport, and deposition [PDF]

open access: yes, 2007
Sea salt and mineral dust records as represented by Na+ and Ca2+ concentrations, respectively, in Greenland and Antarctic ice cores show pronounced glacial/interglacial variations. For the Last Glacial Maximum (LGM) mineral dust (sea salt) concentrations
Fischer, Hubertus   +4 more
core   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Impact of Daily Arctic Sea Ice Variability in CAM3.0 during Fall and Winter [PDF]

open access: yes, 2013
Climate projections suggest that an ice-free summer Arctic Ocean is possible within several decades and with this comes the prospect of increased ship traffic and safety concerns.
Bhatt, Uma S.   +4 more
core  

Seasonal Arctic Sea Ice Prediction Using a Newly Developed Fully Coupled Regional Model With the Assimilation of Satellite Sea Ice Observations

open access: yesJournal of Advances in Modeling Earth Systems, 2020
To increase our capability to predict Arctic sea ice and climate, we have developed a coupled atmosphere‐sea ice‐ocean model configured for the pan‐Arctic with sufficient flexibility.
Chao‐Yuan Yang, Jiping Liu, Shiming Xu
doaj   +1 more source

A stratospheric pathway linking a colder Siberia to Barents-Kara Sea sea ice loss

open access: yesScience Advances, 2018
Stratosphere-troposphere dynamical coupling links the Siberian cold winters to sea ice loss over Barents-Kara seas. Previous studies have extensively investigated the impact of Arctic sea ice anomalies on the midlatitude circulation and associated ...
Pengfei Zhang   +6 more
semanticscholar   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

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