Results 181 to 190 of about 2,485,692 (404)

Enhancing transporter activity in heterologous expression systems with SAHA: a 2500‐times more potent and odorless alternative to butyrate

open access: yesFEBS Open Bio, EarlyView.
Heterologous expression of membrane transporters in cultured cells is essential for functional characterization, but is sometimes limited by low activity. Our study compares the HDAC inhibitors butyrate, VPA and SAHA to enhance transport activity. We propose to replace butyrate by SAHA: it is equally effective, devoid of repulsive odor, costs less, and
Svenja Flögel   +4 more
wiley   +1 more source

Evaluation of the ArcIOPS sea ice forecasts during 2021–2023

open access: yesFrontiers in Earth Science
The operational sea ice forecasts from the Arctic Ice Ocean Prediction System (ArcIOPS) during 2021–2023 are validated against satellite-retrieved sea ice concentration and drift data, in situ and reanalyzed sea ice thickness data.
Xi Liang   +5 more
doaj   +1 more source

Sea Ice Thrust Structures [PDF]

open access: bronze, 1958
W. F. Weeks, D. L. Anderson
openalex   +1 more source

An Emergent Sea Ice Floe Size Distribution in a Global Coupled Ocean‐Sea Ice Model

open access: yesJournal of Geophysical Research: Oceans, 2018
Sea ice is composed of discrete floes, which range in size across orders of magnitude. Here we present a model that represents the joint distribution of sea ice thickness and floe size.
L. Roach   +3 more
semanticscholar   +1 more source

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

open access: yesFEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel   +13 more
wiley   +1 more source

Tracking carbon sources through an Arctic marine food web: insights from fatty acids and their carbon stable isotopes [PDF]

open access: yes, 2014
Thesis (Ph.D.) University of Alaska Fairbanks, 2014.Marine production across the Bering-Chukchi continental shelf is influenced by seasonal sea ice dynamics and climatic conditions.
Wang, Shiway, 王小葳
core  

Review of Arctic sea-ice records over the last millennium from modern, historical, and proxy data sources

open access: yesArctic, Antarctic, and Alpine Research
Sea-ice loss and increasing unpredictability have disturbed and harmed Arctic peoples and ecosystems. In addition, studies demonstrate that sea ice plays a key role in climate variability and air–sea CO2 exchanges. Sea-ice data sets provide environmental
Natasha Leclerc, Jochen Halfar
doaj   +1 more source

Improving Met Office seasonal predictions of Arctic sea ice using assimilation of CryoSat-2 thickness

open access: yesThe Cryosphere, 2018
. Interest in seasonal predictions of Arctic sea ice has been increasing in recent years owing, primarily, to the sharp reduction in Arctic sea-ice cover observed over the last few decades, a decline that is projected to continue.
E. Blockley, K. Peterson
semanticscholar   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

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