Results 271 to 280 of about 902,814 (336)

Tunable Synthetic Hydrogel Modulates Hepatic Lineage Specification of Human Liver Organoid

open access: yesAdvanced Functional Materials, EarlyView.
In this study, a synthetic hydrogel is reported that supports the formation of hiPSC‐derived human liver organoids (HLOs). Hepatic lineage specification can be modulated via conjugation of RGD peptide to hydrogel: RGD‐conjugated hydrogels promote cholangiocyte differentiation, whereas RGD‐free hydrogels favor hepatocyte commitment of HLO cells.
Lei Wang   +16 more
wiley   +1 more source

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

open access: yesAdvanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu   +7 more
wiley   +1 more source

Calcium Imparts Advanced Functionalities to Silk Hydrogels for Biofabrication and Biomedical Innovation

open access: yesAdvanced Functional Materials, EarlyView.
The addition of calcium ions to silk fibroin enhances the hydrogel properties and, when combined with visible light crosslinking, enables compatibility with advanced light‐based fabrication techniques. Calcium ions extend the shelf‐life of silk and facilitate the fabrication of multizonal, multilayered constructs for advanced stimuli‐responsive ...
Hien A. Tran   +11 more
wiley   +1 more source

Sea ice records over more than a century at an observatory facing the Okhotsk coast of Hokkaido, Japan. [PDF]

open access: yesSci Data
Toyoda T   +19 more
europepmc   +1 more source

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

open access: yesAdvanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer   +7 more
wiley   +1 more source

Quasi‐Periodic Surface Functionalization by Ultra‐Short Pulsed Laser Processing: Unlocking Superior Heat Transfer in Vapor Chambers

open access: yesAdvanced Functional Materials, EarlyView.
Ultra‐short pulsed laser processing (ULSP) enables scalable, open‐air fabrication of self‐organized, quasi‐periodic micro/nanostructures on copper using 100 µm laser beams, orders of magnitude larger than the resulting surface features. Integrated into ultra‐thin, wick‐free vapor chambers, these laser‐functionalized surfaces dramatically enhance ...
Anish Pal   +7 more
wiley   +1 more source

Spatiotemporal analysis of sea ice in the Weddell Sea of Antarctic based on GTWR. [PDF]

open access: yesSci Rep
Ding YR   +6 more
europepmc   +1 more source

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