Results 291 to 300 of about 902,814 (336)

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Winter arctic sea ice volume decline: uncertainties reduced using passive microwave-based sea ice thickness. [PDF]

Sci Rep
Soriot C, Vancoppenolle M, Prigent C, Jimenez C, Frappart F.   +4 more
europepmc   +1 more source

Oligohistidine‐Functionalized Single‐Walled Carbon Nanotube‐Guided RNA Delivery to Improve Shoot Regeneration Efficiency in Plant Calli

Advanced Functional Materials, EarlyView.
The pH‐sensitive His6‐SWNTs, which is functionalized with oligohistidine, can deliver STTM396 molecules into callus cells. The STTM396–SWNT complex treatments enhance shoot regeneration efficiency by regulating the miR396‐GRF module in Arabidopsis and tomato calli.
Yeong Yeop Jeong, Hyuna Kwak, Woojin Jeong, Hongwoo Lee, Su‐Ji Jeon, Hyo‐Jun Lee, Pil Joon Seo, Seon‐Yeong Kwak   +7 more
wiley   +1 more source

Field data on sea ice restoration by artificial flooding. [PDF]

Data Brief
Hammer TC, Shestov A, van Dijke LL, Ypma F, Meijeraan T, Hendrikse H.   +5 more
europepmc   +1 more source

Electrochemically Driven Tandem In‐Plane Reduction and FeCl3‐ Intercalation of Highly Crystalline Graphene Oxide Thin Films

Advanced Functional Materials, EarlyView.
This study presents a green processing route for high‐performance reduced graphene oxide (rGO) transparent conductive films (TCFs) using highly crystalline Brodie's GO. In‐plane electrochemical reduction forms rGO on insulating substrates without toxic reductants or heat. Subsequent FeCl₃ intercalation enhances conductivity, overcoming the transparency–
Tatsuki Tsugawa, Kazuto Hatakeyama, Junya Kawasaki, Agamoni Pathak, Kazuhito Tsukagoshi, Shintaro Ida, Takaaki Taniguchi   +6 more
wiley   +1 more source

Pacific sub-decadal sea surface temperature variations contributed to recent Aantarctic Sea ice decline trend. [PDF]

Nat Commun
Wu Q, Ma Y, Hu A, Rosenbloom N, Zhang L, Liu H, Liu S, Yang L, Yang C.   +8 more
europepmc   +1 more source

Enzyme‐Regulated Extended Swelling of Hydrogels for Dehiscence‐Less Tissue Expansions

Advanced Functional Materials, EarlyView.
An interpenetrating hydrogel network with swelling under regulation by enzymatic degradation (INSURED) is fabricated to avoid dehiscence. INSURED remains structurally intact post‐implantation, while HYAL injection enables control over the onset and rate of swelling.
Byung Ik Park, Dong‐yup Lee, Sungsoo Lim, JangHyuk Kim, Min‐Gyu Lee, Chang Seo Park, Hyeonuk Na, Yong Eun Cho, Yun Hyeok Lee, Junsang Doh, Jeong‐Yun Sun   +10 more
wiley   +1 more source

Northern Hemisphere sea ice variability in a transient CGCM simulation of the past 2.6 Ma. [PDF]

Nat Commun
Mandal G, An SI, Park JH, Yun KS, Liu C, Paik S.   +5 more
europepmc   +1 more source

Glutathione and Laccase Dual‐Responsive Lignin Nanocarriers Inspired by Host‐Pathogen Interactions for Fungicide Delivery

Advanced Functional Materials, EarlyView.
Discover bio‐inspired fungicide‐loaded lignin nanocarriers that mimic host‐pathogen interactions, unleashing targeted fungicide release in response to glutathione and laccase. These innovative biobased nanocarriers promise superior crop protection, with increased photostability, enhanced foliar retention, and enabling bidirectional translocation for a ...
Wenlong Liang, Jingli Cheng, Lianmeng Liu, Jinhao Zhao, Frederik R. Wurm   +4 more
wiley   +1 more source