Results 131 to 140 of about 38,499 (290)

Sea ice concentration during POLARSTERN cruise PS93.2

open access: green, 2017
Melanie Bergmann   +5 more
openalex   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

Thermohaline Preconditioning for Sea Ice Formation in the Beaufort Sea

open access: yesGeophysical Research Letters
The influence of ocean stratification and heat content on the timing of sea ice formation and its subsequent growth remains an open question. Here we investigate the thermohaline conditions prior to fall sea ice formation as well as the roles of ...
O. J. Houndegnonto   +5 more
doaj   +1 more source

Vertical ocean heat redistribution sustaining sea-ice concentration trends in the Ross Sea. [PDF]

open access: yesNat Commun, 2017
Lecomte O   +5 more
europepmc   +1 more source

Daily scale Prediction of Arctic Sea Ice Concentration Based on Recurrent Neural Network Models

open access: green, 2023
Juanjuan Feng   +6 more
openalex   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Monitoring of chlorophyll-a concentration in the ice edge zone of the Barents Sea in 2017-2018

open access: diamond, 2019
Veronika V. Vodopianova   +2 more
openalex   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

open access: yesFEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

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