Results 131 to 140 of about 336,668 (362)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

The AutoICE Challenge [PDF]

The Cryosphere
Mapping sea ice in the Arctic is essential for maritime navigation, and growing vessel traffic highlights the necessity of the timeliness and accuracy of sea ice charts.
A. Stokholm, A. Stokholm, J. Buus-Hinkler, T. Wulf, A. Korosov, R. Saldo, L. T. Pedersen, D. Arthurs, I. Dragan, I. Modica, J. Pedro, A. Debien, X. Chen, M. Patel, F. J. P. Cantu, J. N. Turnes, J. Park, L. Xu, K. A. Scott, D. A. Clausi, Y. Fang, M. Jiang, S. Taleghanidoozdoozan, N. C. Brubacher, A. Soleymani, Z. Gousseau, M. Smaczny, P. Kowalski, J. Komorowski, D. Rijlaarsdam, J. N. van Rijn, J. Jakobsen, M. S. J. Rogers, N. Hughes, T. Zagon, R. Solberg, N. Longépé, M. B. Kreiner   +37 more
doaj   +1 more source

AI4SeaIce: selecting loss functions for automated SAR sea ice concentration charting. [PDF]

Sci Rep, 2023
Kucik A, Stokholm A.
europepmc   +1 more source

Pilot study and evaluation of a SMMR-derived sea ice data base [PDF]

Data derived from the Nimbus 7 scanning multichannel microwave radiometer (SMMR) are discussed and the types of problems users have with satellite data are documented. The development of software for assessing the SMMR data is mentioned. Two case studies
Anderson, M. R., Barry, R. G., Crane, R. G., Troisi, V. J., Weaver, R. L.   +4 more
core   +1 more source

A new sea ice albedo scheme including melt ponds for ECHAM5 general circulation model [PDF]

, 2009
Today we experience an accelerated melting of sea ice in the Arctic which global circulation models are inadequate to predict. We believe one of the reasons is the shortcomings in the sea ice albedo schemes for these models.
Luthje, M., Pedersen, C., Roeckner, E., Winther, J.   +3 more
core   +1 more source

Mapping Hsp104 interactions using cross‐linking mass spectrometry

FEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak   +3 more
wiley   +1 more source

Arctic Sea Ice and the Mean Temperature of the Northern Hemisphere [PDF]

arXiv, 2017
The importance of snow cover and ice extent in the Northern Hemisphere was recognized by various authors leading to a positive feedback of surface reflectivity on climate. In fact, the retreat of Arctic sea ice is accompanied by enhanced solar input in the Arctic region, i.e. a decrease of the terrestrial albedo.
arxiv  

Author Correction: AI4SeaIce: selecting loss functions for automated SAR sea ice concentration charting. [PDF]

Sci Rep, 2023
Kucik A, Stokholm A.
europepmc   +1 more source

Spatial cross-correlation of Antarctic Sea ice and seabed topography [PDF]

A time series of derived sea ice concentrations as observed about Antarctica by the Nimbus-7 Scanning Multichannel Microwave Radiometer (SMMR) satellite in 1983 is considered.
Deveaux, Richard D., Phelan, Michael J.
core   +1 more source

Dysfunctional tetraspanin 7 (TSP‐7) in Caenorhabditis elegans promotes; increases in average life‐ & health‐span, stress‐induced survival and motility

FEBS Open Bio, EarlyView.
The C. elegans tetraspanin‐7 (tsp‐7) is a homologue of human CD63, which is a negative regulator of autophagy. The C. elegans strain, tm5761, has a dysfunctional (knockout) tsp‐7 gene. When compared to the wild‐type strain, the tm5761 strain shows increased: life‐ and health‐span; thermotolerance, and stress‐induced locomotion.
Brogan Jones, Laurence Seabra, Francesco Michelangeli   +2 more
wiley   +1 more source