Results 161 to 170 of about 38,499 (290)

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

Step-by-Step Validation of Antarctic ASI AMSR-E Sea-Ice Concentrations by MODIS and an Aerial Image [PDF]

, 2020
Qian Shi, Jie Su, Georg Heygster, Jiuxin Shi, Lianzhong Wang, Li Zhu, Quanli Lou, Valentin Ludwig   +7 more
openalex   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source

Analysis of ice concentration in the Kara Sea based on SMOS MIRAS data using machine learning methods

V. V. Tikhonov, D.R. Katamadze, T.A. Alekseeva, E. V. Afanasyeva, Julia Sokolova, I. V. Khvostov, A.N. Romanov   +6 more
openalex   +1 more source

Comparison of sea ice concentrations from ASI, BT and NT2 algorithms with ERA-Interim dataset in the Arctic and Antarctic regions

, 2020
Shuang Liang, Jiangyuan Zeng, Zhen Li
openalex   +1 more source

Sea Ice Concentration Observed Low Microwave Frequency Radiometers

, 2018
POLAR 2018 - XXXV SCAR Meetings and SCAR/IASC Open Science Conference, 19-23 June 2018, Davos, Switzerland.-- 1 page The launch of the Soil Moisture and Ocean Salinity (SMOS) mission, in 2009, marked the dawn of a new type of space-based microwave observations.
Gabarró, Carolina, Gupta, Mukesh, Martínez, Justino, Turiel, Antonio   +3 more
openaire   +1 more source

Understanding the Effect of Resistance Temperature Detector Temperature Controllers on Microstructural Alignment in Magnetic Freeze Casting

Advanced Engineering Materials, EarlyView.
The effect of temperature controllers that are commonly used in freeze‐casting is investigated in this work. Temperature controllers are observed to generate a voltage in the slurry. Microstructural alignment and ultimate compressive strength data show this voltage to interfere with the ability to align the microstructure using magnetic fields ...
Maddie A. Schmitz, Steven E. Naleway
wiley   +1 more source

Intermolecular Interactions as Driving Force of Increasing Multiphoton Absorption in a Perylene Diimide‐Based Coordination Polymer

Advanced Functional Materials, EarlyView.
This study uncovers the unexplored role of intermolecular interactions in multiphoton absorption in coordination polymers. By analyzing [Zn2tpda(DMA)2(DMF)0.3], it shows how the electronic coupling of the chromophores and confinement in the MOF enhance two‐and three‐photon absorption.
Simon Nicolas Deger, Anna Mauri, Yang Cui, Sebastian Josef Weishäupl, Ali Deniz Özdemir, Hamad Syed, Aleksandr Ovsianikov, Wolfgang Wenzel, Alexander Pöthig, Jürgen Hauer, Mariana Kozlowska, Roland Augustinus Fischer   +11 more
wiley   +1 more source

Modelling plastic concentrations in sea ice and the water column

, 2020
Morales Maqueda, Mountford
openalex   +1 more source