Results 171 to 180 of about 288,973 (326)

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

open access: yesFEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel   +9 more
wiley   +1 more source

Effect of ice algal community on the increase of chlorophyll a concentration during spring in coastal water of the Sea of Okhotsk [PDF]

open access: yes, 2000
A seasonal study of size fractionated chlorophyll α concentration was conducted weekly in Monbetsu Harbor from October 1996 to November 1997 to investigate the annually persistent occurrence of the spring peak of the chlorophyll α concentration in the ...
Fumio Satoh   +5 more
core   +1 more source

Assessment of SMOS measurements of Arctic Sea Ice Concentration

open access: yes, 2016
[1] Font, J.; Camps, A.; Borges, A.; Martin-Neira, M.; Boutin, J.; Reul, N.; Kerr, Y.; Hahne, A. & Mecklenburg, S. SMOS: The Challenging Sea Surface Salinity Measurement From Space Proceedings of the IEEE, no. 5, 2010, 98, 649 -665 [2] Kerr, Y.; Waldteufel, P.; Wigneron, J. P..; Delwart, S.; Cabot, F.; Boutin, J.; Escorihuela, M.J..; Font, J.; Reul, N.;
Gabarró, Carolina   +4 more
openaire   +2 more sources

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

open access: yesFEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama   +7 more
wiley   +1 more source

Improved Simulation of Antarctic Sea Ice by Parameterized Thickness of New Ice in a Coupled Climate Model

open access: yesGeophysical Research Letters
Sea ice formation over open water exerts critical control on polar atmosphere‐ocean‐ice interactions, but is only crudely represented in sea ice models. In this study, a collection depth parameterization of new ice for flux polynya models is modified by ...
Yongjie Fang   +4 more
doaj   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

open access: yesFEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez   +5 more
wiley   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

open access: yesFEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul   +3 more
wiley   +1 more source

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