Results 251 to 260 of about 288,973 (326)

Sea ice extent, concentration, and seasonality [in “State of the Climate in 2019'] [PDF]

, 2020
Phillip Reid, Sharon Stammerjohn, Robert A. Massom, Sandra Barreira, T. A. Scambos, JL Lieser   +5 more
openalex  

Reconfigurable Nucleic Acid Nanoparticles with Therapeutic RNAi Responses to Intracellular Disease Markers

Advanced Functional Materials, EarlyView.
Many known diseases arise from dysregulated gene expression, and differentially expressed genes can serve as biomarkers to distinguish diseased cells from healthy tissues. In this study, reconfigurable nucleic acid nanoparticles (recNANPs) are introduced that can detect overexpressed cancer biomarkers and subsequently release RNAi inducers to silence ...
Yelixza I. Avila, Anh Ha, Morgan R. Chandler, Nathalia Leal Santos, Taejin Kim, Hannah S. Newton, Marina A. Dobrovolskaia, Kirill A. Afonin   +7 more
wiley   +1 more source

Southern Ocean evidence for recurring West Antarctic Ice Sheet destabilization during Marine Isotope Stage 11. [PDF]

Nat Commun
Jebasinski L, Frick DA, Kapuge AKIU, Basak C, Saavedra-Pellitero M, Winckler G, Lamy F, Gottschalk J.   +7 more
europepmc   +1 more source

Prediction of monthly Arctic sea ice concentration using satellite and reanalysis data based on convolutional neural networks

, 2019
Young Jun Kim, Hyun‐Cheol Kim, Daehyeon Han, Sanggyun Lee, Jungho Im   +4 more
openalex   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Environmental Features Associated With At-Sea Sightings of Snow Petrel <i>Pagodroma nivea</i> in East Antarctica. [PDF]

Ecol Evol
Viola B, Halpin L, Fierro-Arcos D, Travers T, Emmerson L, Southwell C, Virtue P, Kelly N, Corney S.   +8 more
europepmc   +1 more source

Comparison of the sea surface temperatures and sea ice concentration from ERA-Interim and BSH [PDF]

, 2010
Cesko, T., Getzlaff, Klaus, Jacob, D., Lehmann, Andreas, Raub, T.   +4 more
core  

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

Advanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao, Tong Ye, Mingjiang Liu, Jingchao Gao, Lian Tan, Qian Dong, Qingbo Lv, Qianqian Ye, Yu Wang   +8 more
wiley   +1 more source

Tunable Synthetic Hydrogel Modulates Hepatic Lineage Specification of Human Liver Organoid

Advanced Functional Materials, EarlyView.
In this study, a synthetic hydrogel is reported that supports the formation of hiPSC‐derived human liver organoids (HLOs). Hepatic lineage specification can be modulated via conjugation of RGD peptide to hydrogel: RGD‐conjugated hydrogels promote cholangiocyte differentiation, whereas RGD‐free hydrogels favor hepatocyte commitment of HLO cells.
Lei Wang, Lasse Riediger, Qi Rao, Xun Xu, Yan Nie, Yiduo Zhou, Junyao Zhang, Peng Tang, Weiwei Wang, Frank Tacke, Adrien Guillot, Ludovic Vallier, Irene Talon, Wenzhong Li, Yi‐An Yang, Rainer Haag, Nan Ma   +16 more
wiley   +1 more source

On the Modeling of Nonlinear Wind-Induced Ice-Drift Ocean Currents at the North Pole. [PDF]

J Math Fluid Mech
Puntini C.
europepmc   +1 more source