Results 261 to 270 of about 283,051 (325)

Tunable Synthetic Hydrogel Modulates Hepatic Lineage Specification of Human Liver Organoid

Advanced Functional Materials, EarlyView.
In this study, a synthetic hydrogel is reported that supports the formation of hiPSC‐derived human liver organoids (HLOs). Hepatic lineage specification can be modulated via conjugation of RGD peptide to hydrogel: RGD‐conjugated hydrogels promote cholangiocyte differentiation, whereas RGD‐free hydrogels favor hepatocyte commitment of HLO cells.
Lei Wang, Lasse Riediger, Qi Rao, Xun Xu, Yan Nie, Yiduo Zhou, Junyao Zhang, Peng Tang, Weiwei Wang, Frank Tacke, Adrien Guillot, Ludovic Vallier, Irene Talon, Wenzhong Li, Yi‐An Yang, Rainer Haag, Nan Ma   +16 more
wiley   +1 more source

Temporary Absence of Warming in the Northern Weddell Sea Validates Expected Responses of Antarctic Seals to Sea Ice Change. [PDF]

Glob Chang Biol
Dunn MJ, Waluda CM, Adlard S, Fox D, Lynnes AS, Morley TI, Forcada J.   +6 more
europepmc   +1 more source

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

Bowhead whale faeces link increasing algal toxins in the Arctic to ocean warming. [PDF]

Nature
Lefebvre KA, Charapata P, Stimmelmayr R, Lin P, Pickart RS, Hubbard KA, Bill BD, Sheffield G, Bowers EK, Anderson DM, Fachon E, Thoman R.   +11 more
europepmc   +1 more source

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

Advanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer, Joanna M. Sadowska, Nadia Roumans, Christian Plank, Christopher H. Evans, Fergal J. O'Brien, Martijn van Griensven, Elizabeth R. Balmayor   +7 more
wiley   +1 more source

21st Century Sea Ice Loss Will Upend 11,700 Years of Stable Habitat for Bowhead Whales. [PDF]

Ecol Evol
Freymueller NA, Lorenzen ED, Brown SC, Rahbek C, Fordham DA.   +4 more
europepmc   +1 more source

Quasi‐Periodic Surface Functionalization by Ultra‐Short Pulsed Laser Processing: Unlocking Superior Heat Transfer in Vapor Chambers

Advanced Functional Materials, EarlyView.
Ultra‐short pulsed laser processing (ULSP) enables scalable, open‐air fabrication of self‐organized, quasi‐periodic micro/nanostructures on copper using 100 µm laser beams, orders of magnitude larger than the resulting surface features. Integrated into ultra‐thin, wick‐free vapor chambers, these laser‐functionalized surfaces dramatically enhance ...
Anish Pal, Arani Mukhopadhyay, Graham Kaufman, Suchit Sarin, Jeffrey E. Shield, George Gogos, Craig Zuhlke, Constantine M. Megaridis   +7 more
wiley   +1 more source

Impacts of Antarctic summer sea-ice extremes. [PDF]

PNAS Nexus
Doddridge EW, Hobbs WR, Auger M, Boyd PW, Chua SMT, Cook S, Corney S, Emmerson L, Fraser AD, Heil P, Kelly N, Lannuzel D, Li X, Liniger G, Massom RA, Meyer A, Reid P, Southwell C, Spence P, Steketee A, Swadling KM, Teder N, Wienecke B, Wongpan P, Yamazaki K.   +24 more
europepmc   +1 more source

Bio‐Responsive Hydrogel for Targeted on‐Demand Release of a Phage Cocktail for Treatment of Pseudomonas aeruginosa Infection

Advanced Functional Materials, EarlyView.
This study presents an injectable hydrogel that responds to Pseudomonas aeruginosa infection by releasing a dual‐phage cocktail on demand. The system degrades selectively in infected wounds, enhances phage localization and stability, and shows potent antibiofilm activity and biocompatibility in an ex vivo human skin model—offering a promising strategy ...
Siyuan Tao, Anna Hu, Elnaz Bavel, Chien‐Hsun Yu, Sixuan Zhang, Vera Maria Kissling, Zhihao Li, Thomas Fintan Moriaty, Katharina Maniura‐Weber, Qun Ren   +9 more
wiley   +1 more source

A comprehensive characterisation of natural aerosol sources in the high Arctic during the onset of sea ice melt.

Faraday Discuss
Freitas GP, Kojoj J, Mavis C, Creamean J, Mattsson F, Nilsson L, Schmidt JS, Adachi K, Šantl-Temkiv T, Ahlberg E, Mohr C, Riipinen I, Zieger P.   +12 more
europepmc   +1 more source