Results 301 to 310 of about 336,668 (362)

Marine ecosystem role in setting up preindustrial and future climate. [PDF]

Nat Commun
Tjiputra JF, Couespel D, Sanders R.
europepmc   +1 more source

TPMS‐Gyroid Scaffold‐Mediated Up‐Regulation of ITGB1 for Enhanced Cell Adhesion and Immune‐Modulatory Osteogenesis

Advanced Healthcare Materials, EarlyView.
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang, Zenan Huang, Zhenzhong Han, Jing Luan, Zihan Li, Xutong Guo, Dongxu Yang, Yazhou Cui, Jinxiang Han, Duo Xu   +9 more
wiley   +1 more source

Anthropogenic intensification of Arctic anticyclonic circulation. [PDF]

Sci Adv
Liu Z, Risi C, Codron F, Gastineau G, Huan X, Lan H, Xu W, Bowen GJ.   +7 more
europepmc   +1 more source

Morphometric‐Assisted Prediction of Developmental Toxicity Using Stem Cell‐Based Embryo Models in Microwells

Advanced Healthcare Materials, EarlyView.
This proof‐of‐concept study involves high‐throughput teratogenicity screening of compounds using XEn/EpiCs, a 3D stem cell‐based embryo model, within microwells. The term ‘morphotoxicity’ is introduced to complement traditional cytotoxicity assays through automated feature extraction and machine‐learning‐assisted classification of morphologies.
Vinidhra Shankar, Athanasia Zoi Pappa, Clemens van Blitterswijk, Erik Vrij, Stefan Giselbrecht   +4 more
wiley   +1 more source

The time of emergence of Arctic warming, wetting and sea ice melting. [PDF]

Sci Rep
Tsakali N, Kolbe M, Bintanja R, Skyllas N.   +3 more
europepmc   +1 more source

Rod‐shaped Polymerized Salicylic Acid Particles Modulate Neutrophil Transendothelial Migration in Acute Inflammation

Advanced Healthcare Materials, EarlyView.
Rod‐shaped particles outperform spherical particles of the same volume in preventing neutrophil infiltration to inflamed areas, both in vitro and in vivo. This therapeutic effectiveness is attributed to better cell targeting and decreased cell motility, resulting from the geometry‐driven phagocytosis and inhibited actin polymerization.
M. Valentina Guevara, Emma R. Brannon, Daniel Kupor, Mariana R.N. Lima, Logan D. Piegols, Michael L. Felder, Kathryn E. Uhrich, Omolola Eniola‐Adefeso   +7 more
wiley   +1 more source

Wind-triggered Antarctic sea ice decline preconditioned by thinning Winter Water

Spira T, du Plessis M, Haumann FA, Giddy I, Narayanan A, Silvano A, Swart S.   +6 more
europepmc   +1 more source

Record-low Antarctic sea ice in 2023 increased ocean heat loss and storms. [PDF]

Nature
Josey SA, Meijers AJS, Blaker AT, Grist JP, Mecking J, Ayres HC.   +5 more
europepmc   +1 more source

Short‐Chain Fatty Acids Modulate Anti‐ROR1 CAR T‐Cell Function and Exhaustion in an Intestinal Adenocarcinoma‐on‐Chip Model

Advanced Healthcare Materials, EarlyView.
Short‐chain fatty acids modulate anti‐ROR1 chimeric antigen receptor (CAR) T‐cell function in an intestinal adenocarcinoma‐on‐chip model. Butyrate and propionate reduce cytotoxicity, cytokine release, and infiltration by inducing a regulatory T‐cell phenotype and T‐cell exhaustion via histone deacetylase inhibition.
Valentin D. Wegner, Adrian Feile, Miriam Alb, Michael Hudecek, Philip Hewitt, Alexander S. Mosig   +5 more
wiley   +1 more source

Attenuation of progressive surface gravity waves by floating spheres. [PDF]

Sci Rep
Calvert R, Mol J, Sutherland BR, van den Bremer TS.   +3 more
europepmc   +1 more source