Results 301 to 310 of about 176,859 (335)

Sea level since the Last Glacial Maximum from the Atlantic coast of Africa. [PDF]

Nat Commun
Vacchi M, Shaw TA, Anthony EJ, Spada G, Melini D, Li T, Cahill N, Horton BP.   +7 more
europepmc   +1 more source

Lipid Droplet‐Derived Biomimetic Nanocarriers for the Enhancement of Porcine Intermuscular Fat Content

Advanced Science, EarlyView.
The article presents the development of artificial lipid droplets (aLDs) as biomimetic nanocarriers to enhance intramuscular fat (IMF) content in pigs. These aLDs, loaded with oleic acid, significantly increase IMF by up to 35% in muscle tissues without adverse side effects. This innovative approach improves pork quality by enhancing marbling, offering
Pengxiang Zhao, Hongbo Han, Jingjie Hao, Ziwei Yu, Zichen Zhao, Lupeng Chen, Heng Wang, Jian Wu, Zhuqing Ren   +8 more
wiley   +1 more source

A comprehensive characterisation of natural aerosol sources in the high Arctic during the onset of sea ice melt.

Faraday Discuss
Freitas GP, Kojoj J, Mavis C, Creamean J, Mattsson F, Nilsson L, Schmidt JS, Adachi K, Šantl-Temkiv T, Ahlberg E, Mohr C, Riipinen I, Zieger P.   +12 more
europepmc   +1 more source

Lessened projections of Arctic warming and wetting after correcting for model errors in global warming and sea ice cover. [PDF]

Sci Adv
Cai Z, You Q, Screen JA, Chen HW, Zhang R, Zuo Z, Chen D, Cohen J, Kang S, Zhang R.   +9 more
europepmc   +1 more source

Bioprinted Patient‐Derived Organoid Arrays Capture Intrinsic and Extrinsic Tumor Features for Advanced Personalized Medicine

Advanced Science, EarlyView.
An embedded bioprinting enabled‐arrayed patient‐derived organoids (Eba‐PDO) platform that replicates intrinsic and extrinsic tumor characteristics is introduced. Eba‐PDOs more accurately mimic tissue than standard PDOs (Std‐PDOs) due to maturation in the tumor microenvironment.
Jonghyeuk Han, Hye‐Jin Jeong, Jeonghan Choi, Hyeonseo Kim, Taejoon Kwon, Kyungjae Myung, Kyemyung Park, Jung In Park, Samuel Sánchez, Deok‐Beom Jung, Chang Sik Yu, In Ho Song, Jin‐Hyung Shim, Seung‐Jae Myung, Hyun‐Wook Kang, Tae‐Eun Park   +15 more
wiley   +1 more source

Subsurface warming associated with Pacific Summer Water transport toward the Chukchi Borderland in the Arctic Ocean. [PDF]

Sci Rep
Muramatsu M, Watanabe E, Itoh M, Onodera J, Mizobata K, Ueno H.   +5 more
europepmc   +1 more source

PCSK9 Promotes the Malignancy of Triple‐negative Breast Cancer Cells by Reducing Cholesterol Levels at the Plasma Membrane to Activate EGFR and HER3

Advanced Science, EarlyView.
By decreasing cholesterol and lipid raft levels in the plasma membrane, proprotein convertase subtilisin/kexin type 9 (PCSK9) boosts human epidermal growth factor receptor 1 and 3 (EGFR and HER3) activation, driving tumor growth and metastasis in triple‐negative breast cancer (TNBC).
Tianhong Li, Renfei Wu, Kathy Qian Luo
wiley   +1 more source

Global mean sea level likely higher than present during the holocene. [PDF]

Nat Commun
Creel RC, Austermann J, Kopp RE, Khan NS, Albrecht T, Kingslake J.   +5 more
europepmc   +1 more source

Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization

Advanced Science, EarlyView.
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao, Yule Yong, Zhaohui Zheng, Kui Zhang, Wei Li, Jiayi Liu, Siyi Zhou, Juan‐juan Qin, Haoyang Sun, Yatao Wang, Xianghui Fu, Xing Luo, Siyu Chen, Zhi‐Gang She, Jingjing Cai, Ping Zhu   +15 more
wiley   +1 more source

A 430 kyr record of ice-sheet dynamics and organic-carbon burial in the central Eurasian Arctic Ocean. [PDF]

Nat Commun
Stein R, Frederichs T, Fahl K, Geibert W, Matthiessen J, Niessen F, Vogt C, Sassenroth C, Bazhenova E.   +8 more
europepmc   +1 more source