ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
Sea-Level Fingerprints Due to Present-Day Water Mass Redistribution in Observed Sea-Level Data
Satellite altimetry over the oceans shows that the rate of sea-level rise is far from uniform, with reported regional rates up to two to three times the global mean rate of rise of ~3.3 mm/year during the altimeter era.
Lorena Moreira +3 more
doaj +1 more source
Should Swedish sea level planners worry more about mean sea level rise or sea level extremes?
AbstractCurrent coastal spatial planning in Sweden uses simple methods to account for how flood risks increase owing to sea level rise. Those methods, however, fail to account for several important aspects of sea level rise, such as: projection uncertainty, emission scenario uncertainty and time dependence. Here, enhanced methods that account for these
Magnus Hieronymus, Ola Kalén
openaire +3 more sources
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman +8 more
wiley +1 more source
Sea level rise adaptation: emerging lessons for local policy development [PDF]
Many coastal communities across the United States are beginning to plan for climate-related sea level rise. While impacts and solutions will vary with local conditions, jurisdictions which have begun this process seem to pass through three common stages ...
Lausche, Barbara J., Maier, Luke
core
Impact of the Caspian Sea Level Fluctuation on Ground Water Regime and Functioning of the Hydro-Reclamation Network on the Caspian Side Zones [PDF]
An aim of the research is to investigate an impact of the Caspian Sea level fluctuations on the ground water regime and functioning of the hydro-meliorative network on the Caspian side zone, including Mugan- Salyan region.
Gurbanov, M. F. (M), Mammadli, A. A. (A)
core +1 more source
Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul +13 more
wiley +1 more source
Comparing built-up area datasets to assess urban exposure to coastal hazards in Europe
Information on urban land use, beyond the urban-rural dichotomy, can improve the assessment of potential impacts of coastal hazards by refining estimates of damages and supporting adaptation planning.
Hedda Bonatz +2 more
doaj +1 more source
Non-linear interaction modulates global extreme sea levels, coastal flood exposure, and impacts
The non-linear interaction between tide and non-tidal residual impacts current and future extreme water levels. Here, based on 620 gauge records, the authors find a large non-linear interaction in the US East Coast, North Sea and parts of southern Japan,
Arne Arns +7 more
doaj +1 more source
The Land-Sea Warming Contrast as the Driver of Tropical Sea Level Pressure Changes [PDF]
In this presentation we address the causes of the large-scale tropical sea level pressure (SLP) changes during climate change. The analysis we present is based on climate change model simulations, observed trends and the seasonal cycle.
Bayr, Tobias, Dommenget, Dietmar
core

