Results 81 to 90 of about 66,031 (308)

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Evidence of Road Salt in New Hampshire’s Snowpack Hundreds of Meters from Roadways

Geosciences, 2017
Salinization of surface and groundwater has been directly linked to the area of road surfaces in a watershed and the subsequent wintertime maintenance used to keep roads free of snow and ice.
James Lazarcik, Jack E. Dibb
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Microplastics in Table Salts: Sources, Abundance, Types, and Consumption– A Review

Pakistan Journal of Analytical & Environmental Chemistry
Microplastics (MPs) exist everywhere, from the bottom of the ocean to the peak of mountains, and pose a significant threat to species and habitats. These tiny plastic particles have polluted all components of the biosphere, including both biotic and ...
Fatima Kanwal, Zafar Iqbal Shams
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Arctic warming by abundant fine sea salt aerosols from blowing snow. [PDF]

Nat Geosci, 2023
Gong X, Zhang J, Croft B, Yang X, Frey MM, Bergner N, Chang RY, Creamean JM, Kuang C, Martin RV, Ranjithkumar A, Sedlacek AJ, Uin J, Willmes S, Zawadowicz MA, Pierce JR, Shupe MD, Schmale J, Wang J.   +18 more
europepmc   +1 more source

Depth Imaging Sub-salt Structures: A Case Study in the Midyan Peninsula (Red Sea) [PDF]

, 1999
D. Mougenot, Amir A. Al-Shakhis
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Jacalin-related lectin 45 (OsJRL45) isolated from ‘sea rice 86’ enhances rice salt tolerance at the seedling and reproductive stages [PDF]

, 2023
Qinmei Gao, Xiaolin Yin, Feng Wang, Congzhi Zhang, Feicui Xiao, Hongyan Wang, Shuchang Hu, Weihao Liu, Shiqi Zhou, Liang-Bi Chen, Xiaojun Dai, Manzhong Liang   +11 more
openalex   +1 more source